Sugi Predict

Sugi Predict / Compounds / SCHEMBL875085

SCHEMBL875085

SCHEMBL875085

O=C1N[C@H]2[C@H](CS[C@H]2CCCC(S)C(=O)O)N1

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.64
▸ MEN1 O00255 1/20 0.64
▸ ABL1 P00519 1/20 0.64
▸ LMNA P02545 1/20 0.64
▸ PKM P14618 1/20 0.64
▸ IDE P14735 1/20 0.64
▸ MAPK1 P28482 1/20 0.64
▸ KMT2A Q03164 1/20 0.64
▸ RIN1 Q13671 1/20 0.64
▸ L3MBTL1 Q9Y468 1/20 0.64
▸ HLCS P50747 6/20 0.59
▸ CA12 O43570 5/20 0.44
▸ CA1 P00915 5/20 0.44
▸ CA2 P00918 5/20 0.44
▸ CA9 Q16790 5/20 0.44
▸ FOLH1 Q04609 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487045 0.88 TDP1 (0.68) TDP1MEN1ABL1LMNAPKM
SCHEMBL5592430 0.87 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM
SCHEMBL425273 0.86 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
SCHEMBL6036962 0.85 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM
SCHEMBL1936659 0.85 TDP1 (0.65) TDP1MEN1ABL1LMNAPKM
SCHEMBL629531 0.84 TDP1 (0.74) TDP1MEN1ABL1LMNAPKM
SCHEMBL29959220 0.84 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM
SCHEMBL8534380 0.84 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM
SCHEMBL5551259 0.84 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM
SCHEMBL29884470 0.84 TDP1 (0.64) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118746688-A Preparation method and application of giant magneto-resistance biosensor based on amorphous wire array 浙江大学 2024-10-08 — — CN claimed
US-9395371-B2 Synthesis of fluorescent noble metal nanoparticles THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2016-07-19 — — US claimed
US-20130183665-A1 SYNTHESIS OF FLUORESCENT NOBLE METAL NANOPARTICLES THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2013-07-18 — — US claimed
WO-2012037667-A1 SYNTHESIS OF FLUORESCENT NOBLE METAL NANOPARTICLES THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2012-03-29 — — WO claimed
CN-113980089-B Method for detecting cell outer membrane vesicles in sample and application of detection kit 富士胶片株式会社 2024-12-27 — — CN disclosed
CN-119000210-A Method for enriching RNA binding protein in mammal tissue in large scale and identification method thereof 中国中医科学院医学实验中心 2024-11-22 — — CN disclosed
CN-118746688-A Preparation method and application of giant magneto-resistance biosensor based on amorphous wire array 浙江大学 2024-10-08 — — CN disclosed
CN-113640511-B Magnetic particle electrochemiluminescence kit 宁波瑞源生物科技有限公司 2024-01-30 — — CN disclosed
CN-110741248-B Chip-based multichannel electrochemical converter and method of use thereof 亿皮米特瑞克斯公司 2023-05-30 — — CN disclosed
US-20230145835-A1 Modulators of Alpha-4-beta-7 Integrin and MAdCAM QUANTUM INTELLIGENCE CORP. (KR) 2023-05-11 — — US disclosed
CN-110178033-B Low energy cleavable mass tags for quantitative proteomics 马克斯-普朗克科学促进学会 2023-04-14 — — CN disclosed
WO-2023056560-A1 MODULATORS OF ALPHA-4-BETA-7 INTEGRIN AND MADCAM 48HD BIOPHARMA INC. (CA) 2023-04-13 — — WO disclosed
WO-2013049409-A2 SUBSTRATES HAVING NANOSTRUCTURES HAVING BIOLOGICAL SPECIES IMMOBILIZED THEREON AND METHODS OF FORMING THE SAME AND METHODS OF FORMING NANOSTRUCTURES ON SURFACES NORTHWESTERN UNIVERSITY (US) 2013-04-04 — — WO disclosed
WO-2012037667-A1 SYNTHESIS OF FLUORESCENT NOBLE METAL NANOPARTICLES THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2012-03-29 — — WO disclosed
WO-2012037667-A1 SYNTHESIS OF FLUORESCENT NOBLE METAL NANOPARTICLES THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2012-03-29 — — WO disclosed
US-20060194346-A1 Surface plasmon-field-enhanced diffraction sensor MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2006-08-31 — — US disclosed
EP-1566627-A1 Surface plasmon field-enhanced diffraction sensor Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2005-08-24 — — EP disclosed
US-20050014784-A1 Endostatin-like angiogenesis inhibition MINERVA BIOTECHNOLOGIES CORPORATION (US) 2005-01-20 — — US disclosed
US-20020156112-A1 Endostatin-like angiogenesis inhibition MINERVA BIOTECHNOLOGIES CORPORATION 2002-10-24 — — US disclosed
WO-2002039999-A2 USE OF SURAMINE, L-HISTIDINE, QUISQUALIC ACID OR D-CYCLOSERINE FOR ANGIOGENESIS INHIBITION MINERVA BIOTECHNOLOGIES CORPORATION (US) 2002-05-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230145835-A1 Modulators of Alpha-4-beta-7 Integrin and MAdCAM ITGB7, ITGAM, ITGA4 TDP1 3805/4885MEN1 1008/4885ABL1 1092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.