SCHEMBL87510

SCHEMBL87510

C=CCN(C=O)CCN(CC=C)CC=C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24833 0.79
SCHEMBL127488 0.79 TSHR (0.38) SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL9578963 0.78
Hydrochloric Acid SCHEMBL4378364 0.76 ALDH1A1 (0.33)
Ammonia Solution, Strong SCHEMBL8814151 0.76 ALDH1A1 (0.33)
SCHEMBL11373054 0.76
SCHEMBL11374158 0.76
Hydrochloric Acid SCHEMBL9501246 0.76 OPRK1 (0.36) SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL6528243 0.76 OPRK1 (0.38) SMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL27095801 0.76 KMT2A (0.35) SMN1; SMN2KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067584-B2 Benzothiazepine derivatives ALBIREO AB (SE) 2011-11-29 US claimed
EP-1539743-B1 PYRAZOLE DERIVATIVES AS GNRH INHIBITORS ASTRAZENECA AB (SE) 2007-05-30 EP claimed
US-6362191-B1 ANTIBIOTICS ZENECA LTD. (GB) 2002-03-26 US claimed
WO-2024140970-A1 BICYCLIC COMPOUND, AND PREPARATION METHOD AND USE THEREFOR 广州市联瑞制药有限公司 2024-07-04 WO disclosed
WO-2024140969-A1 TRICYCLIC COMPOUND, AND PREPARATION METHOD AND USE THEREFOR 广州市联瑞制药有限公司 2024-07-04 WO disclosed
WO-2024140968-A1 TRICYCLIC COMPOUND, AND PREPARATION METHOD AND USE THEREFOR 广州市联瑞制药有限公司 2024-07-04 WO disclosed
WO-2024140971-A1 BICYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF 广州市联瑞制药有限公司 2024-07-04 WO disclosed
US-12023319-B2 Carboxylic acid aromatic amides BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2024-07-02 US disclosed
CN-118271300-A Lactam compound, and preparation method and application thereof 广州市联瑞制药有限公司 2024-07-02 CN disclosed
CN-118271299-A Lactam compound, and preparation method and application thereof 广州市联瑞制药有限公司 2024-07-02 CN disclosed
US-12006311-B2 Compounds for use in preventing or treating cancer FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRONINSTITUT DE RECERCA (ES) 2024-06-11 US disclosed
EP-0882042-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES AstraZeneca UK Limited (GB) 1998-12-09 EP disclosed
US-5834468-A ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, ANALGESICS TREATING RHEUMATIC DISEASE, BONE DISORDER, INJURIES ZENECA LIMITED (GB) 1998-11-10 US disclosed
WO-1997043280-A1 3-PHENYL-FURAN-(5H)-2-ONE AND DIHYDROFURAN-2-ONE DERIVATIVES AS ANTIBACTERIAL AGENTS ZENECA LIMITED (GB) 1997-11-20 WO disclosed
WO-1997031917-A9 SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS 1997-10-30 WO disclosed
WO-1997031917-A1 SUBSTITUTED PHENYLOXAZOLIDINONES AND THEIR USE AS ANTIBIOTICS ZENECA LIMITED (GB) 1997-09-04 WO disclosed
WO-1997030995-A1 ANTIBIOTIC OXAZOLIDINONE DERIVATIVES ZENECA LIMITED (GB) 1997-08-28 WO disclosed
WO-1997000863-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ZENECA LIMITED (GB) 1997-01-09 WO disclosed
WO-1997000864-A1 AROMATIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ZENECA LIMITED (GB) 1997-01-09 WO disclosed
EP-0752421-A1 Ortho-substituted aromatic compounds, containing three (het)aryl moieties, their preparation and their use as prostaglandin E2-(PGE2)-antagonists ZENECA LIMITED (GB) 1997-01-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12023319-B2 Carboxylic acid aromatic amides DDC, PAH, NAT1 SMN1; SMN2 2568/4885KDM4E 1120/4885MEN1 2258/4885
US-12006311-B2 Compounds for use in preventing or treating cancer UGT1A3, UGT1A1, UGT1A6 SMN1; SMN2 3297/4885KDM4E 1983/4885MEN1 689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.