Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.81 |
| ▸ | FNTB | P49356 | 2/20 | 0.81 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.77 |
| ▸ | LMNA | P02545 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | SHBG | P04278 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989375 | 0.91 | FNTA (0.83) | FNTAFNTBSERPINA6LMNASMN1; SMN2 | |
| SCHEMBL19961198 | 0.91 | FNTA (0.76) | FNTAFNTBSERPINA6LMNASMN1; SMN2 | |
| SCHEMBL141610 | 0.90 | SERPINA6 (0.80) | FNTAFNTBSERPINA6LMNASMN1; SMN2 | |
| SCHEMBL14382323 | 0.90 | SERPINA6 (0.80) | FNTAFNTBSERPINA6LMNASMN1; SMN2 | |
| SCHEMBL13026136 | 0.90 | SERPINA6 (0.80) | FNTAFNTBSERPINA6LMNASMN1; SMN2 | |
| SCHEMBL141611 | 0.90 | SERPINA6 (0.80) | FNTAFNTBSERPINA6LMNASMN1; SMN2 | |
| SCHEMBL20239320 | 0.90 | SERPINA6 (0.80) | FNTAFNTBSERPINA6LMNASMN1; SMN2 | |
| SCHEMBL9073248 | 0.89 | SERPINA6 (0.79) | FNTAFNTBSERPINA6LMNASMN1; SMN2 | |
| SCHEMBL15920543 | 0.87 | SERPINA6 (1.00) | FNTAFNTBSERPINA6LMNASMN1; SMN2 | |
| SCHEMBL668966 | 0.87 | SERPINA6 (1.00) | FNTAFNTBSERPINA6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607088-B1 | New 17,20-epoxy pregnane derivatives, their use in the preparation of cortisone derivatives and intermediates therefor | ROUSSEL UCLAF (FR) | 1997-04-09 | — | — | EP | disclosed |
| EP-0607088-A1 | New 17,20-epoxy pregnane derivatives, their use in the preparation of cortisone derivatives and intermediates therefor | ROUSSEL UCLAF (FR) | 1994-07-20 | — | — | EP | disclosed |