SCHEMBL20239320

SCHEMBL20239320

C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@H]2C(=O)CO

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SERPINA6 P08185 6/20 0.80
▸ FNTA P49354 1/20 0.75
▸ FNTB P49356 1/20 0.75
▸ SMN1; SMN2 Q16637 9/20 0.72
▸ LMNA P02545 8/20 0.72
▸ ALDH1A1 P00352 7/20 0.72
▸ CYP3A4 P08684 7/20 0.72
▸ HSD17B10 Q99714 5/20 0.72
▸ SHBG P04278 5/20 0.72
▸ MAPT P10636 5/20 0.72
▸ MAPK1 P28482 4/20 0.72
▸ ABCB11 O95342 2/20 0.72
▸ HIF1A Q16665 4/20 0.67
▸ TSHR P16473 4/20 0.67
▸ CYP2C9 P11712 3/20 0.67
▸ NR3C2 P08235 3/20 0.67
▸ SLC22A2 O15244 2/20 0.67
▸ SLC22A1 O15245 2/20 0.67
▸ SLC22A3 O75751 2/20 0.67
▸ THPO P40225 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13026136 1.00 SERPINA6 (0.80) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL14382323 1.00 SERPINA6 (0.80) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL141611 1.00 SERPINA6 (0.80) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL141610 1.00 SERPINA6 (0.80) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL9073248 0.91 SERPINA6 (0.79) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL8751542 0.90 FNTA (0.81) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL668966 0.89 SERPINA6 (1.00) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL15904593 0.89 SERPINA6 (1.00) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL14525642 0.89 SERPINA6 (1.00) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL15920543 0.89 SERPINA6 (1.00) SERPINA6FNTAFNTBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12553041-B2 Formulations and doses of pegylated uricase Cartesian Therapeutics Inc. (US) 2026-02-17 — — US disclosed
US-20260021113-A1 INTRAVITREAL CORTICOSTEROID EXTENDED RELEASE IMPLANT AND METHODS OF USE EYEDEA BIO LLC (US) 2026-01-22 — — US disclosed
US-12433900-B2 Intravitreal corticosteroid extended release implant and methods of use EYEDEA BIO, LLC (US) 2025-10-07 — — US disclosed
EP-4599848-A2 METHODS AND COMPOSITIONS RELATED TO COMBINED TREATMENT WITH ANTI-INFLAMMATORIES AND SYNTHETIC NANOCARRIERS COMPRISING AN IMMUNOSUPPRESSANT Cartesian Therapeutics, Inc. (US) 2025-08-13 — — EP disclosed
EP-4595981-A1 ANTIBODY-DRUG CONJUGATES COMPRISING AN ANTI-INTEGRIN V 6 BINDING ANTIBODY Elands, Jack (BE) 2025-08-06 — — EP disclosed
WO-2025132907-A1 NOVEL ANTIBODY-DRUG CONJUGATES COMPRISING AN ANTI-(TCR)-CD3-COMPLEX BINDING ANTIBODY ADCYTHERIX SAS (FR) 2025-06-26 — — WO disclosed
EP-4574174-A1 NOVEL ANTIBODY-DRUG CONJUGATES COMPRISING AN ANTI-(TCR)-CD3-COMPLEX BINDING ANTIBODY Elands, Jack (BE) 2025-06-25 — — EP disclosed
EP-3592389-B1 METHODS AND COMPOSITIONS RELATED TO COMBINED TREATMENT WITH ANTI-INFLAMMATORIES AND SYNTHETIC NANOCARRIERS COMPRISING AN IMMUNOSUPPRESSANT CARTESIAN THERAPEUTICS INC (US) 2025-05-07 — — EP disclosed
US-20250108094-A1 METHODS AND COMPOSITIONS RELATED TO COMBINED TREATMENT WITH ANTI-INFLAMMATORIES AND SYNTHETIC NANOCARRIERS COMPRISING AN IMMUNOSUPPRESSANT CARTESIAN THERAPEUTICS, INC. (US) 2025-04-03 — — US disclosed
US-20250090451-A1 FORMULATIONS AND DOSES OF PEGYLATED URICASE CARTESIAN THERAPEUTICS, INC. (US) 2025-03-20 — — US disclosed
US-20180168490-A1 INGESTIBLE DEVICE AND ASSOCIATED METHODS GLAS USA LLC 2018-06-21 — — US disclosed
WO-2018112389-A1 INGESTIBLE DEVICE AND ASSOCIATED METHODS PROGENITY INC. (US) 2018-06-21 — — WO disclosed
WO-2018112441-A1 INGESTIBLE DEVICE AND ASSOCIATED METHODS PROGENITY INC. (US) 2018-06-21 — — WO disclosed
WO-2018111326-A1 METHODS AND INGESTIBLE DEVICES FOR THE REGIO-SPECIFIC RELEASE OF IMMUNOSUPPRESSANTS AT THE SITE OF GASTROINTESTINAL TRACT DISEASE PROGENITY INC. (US) 2018-06-21 — — WO disclosed
WO-2018112425-A1 INGESTIBLE DEVICE AND ASSOCIATED METHODS PROGENITY INC. (US) 2018-06-21 — — WO disclosed
WO-2018106931-A1 GASTROINTESTINAL TRACT DETECTION METHODS, DEVICES AND SYSTEMS PROGENITY INC. (US) 2018-06-14 — — WO disclosed
WO-2018106933-A1 GASTROINTESTINAL TRACT DETECTION METHODS, DEVICES AND SYSTEMS PROGENITY INC. (US) 2018-06-14 — — WO disclosed
WO-2018106945-A1 GASTROINTESTINAL TRACT DETECTION METHODS, DEVICES AND SYSTEMS PROGENITY INC. (US) 2018-06-14 — — WO disclosed
US-20180164221-A1 GASTROINTESTINAL TRACT DETECTION METHODS, DEVICES AND SYSTEMS BT BIDCO LLC 2018-06-14 — — US disclosed
WO-2018106959-A1 GASTROINTESTINAL TRACT DETECTION METHODS, DEVICES AND SYSTEMS PROGENITY INC. (US) 2018-06-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12553041-B2 Formulations and doses of pegylated uricase PON1, PNP, PCSK9 SERPINA6 43/4885FNTA 1204/4885FNTB 2599/4885
US-20260021113-A1 INTRAVITREAL CORTICOSTEROID EXTENDED RELEASE IMPLANT AND METHODS OF USE NR3C2, NR3C1, STARD3 SERPINA6 173/4885FNTA 1154/4885FNTB 3273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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