SCHEMBL141611

SCHEMBL141611

C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2C(=O)C[C@]2(C)C(C(=O)CO)CC[C@@H]12

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SERPINA6 P08185 6/20 0.80
▸ FNTA P49354 1/20 0.75
▸ FNTB P49356 1/20 0.75
▸ SMN1; SMN2 Q16637 9/20 0.72
▸ LMNA P02545 8/20 0.72
▸ ALDH1A1 P00352 7/20 0.72
▸ CYP3A4 P08684 7/20 0.72
▸ HSD17B10 Q99714 5/20 0.72
▸ SHBG P04278 5/20 0.72
▸ MAPT P10636 5/20 0.72
▸ MAPK1 P28482 4/20 0.72
▸ ABCB11 O95342 2/20 0.72
▸ HIF1A Q16665 4/20 0.67
▸ TSHR P16473 4/20 0.67
▸ CYP2C9 P11712 3/20 0.67
▸ NR3C2 P08235 3/20 0.67
▸ SLC22A2 O15244 2/20 0.67
▸ SLC22A1 O15245 2/20 0.67
▸ SLC22A3 O75751 2/20 0.67
▸ THPO P40225 2/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13026136 1.00 SERPINA6 (0.80) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL14382323 1.00 SERPINA6 (0.80) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL141610 1.00 SERPINA6 (0.80) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL20239320 1.00 SERPINA6 (0.80) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL9073248 0.91 SERPINA6 (0.79) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL8751542 0.90 FNTA (0.81) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL668966 0.89 SERPINA6 (1.00) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL15904593 0.89 SERPINA6 (1.00) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL14525642 0.89 SERPINA6 (1.00) SERPINA6FNTAFNTBSMN1; SMN2LMNA
SCHEMBL15920543 0.89 SERPINA6 (1.00) SERPINA6FNTAFNTBSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260148848-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2026-05-28 — — US claimed
US-20250164507-A1 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CARDIOMYOPATHY IN A FELINE Société des Produits Nestlé S.A. (CH) 2025-05-22 — — US claimed
US-20250041208-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2025-02-06 — — US claimed
EP-4444277-A1 NEW INJECTABLE COMBINATION FORMULATION Nanexa AB (SE) 2024-10-16 — — EP claimed
CN-115015531-B Endogenous marker set and application thereof in evaluation of genistein intake 上海交通大学 2024-09-13 — — CN claimed
CN-118647367-A Novel injectable combination formulations 南爱克萨股份公司 2024-09-13 — — CN claimed
US-20240047065-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF UNIVERSITY OF DUNDEE (GB) 2024-02-08 — — US claimed
CN-117030904-B Method for measuring 144 steroid hormones in environmental sample by liquid chromatography-mass spectrometry 北京林业大学 2023-12-19 — — CN claimed
CN-117030904-A Method for measuring 144 steroid hormones in environmental sample by liquid chromatography-mass spectrometry 北京林业大学 2023-11-10 — — CN claimed
WO-2023105227-A1 NEW INJECTABLE COMBINATION FORMULATION NANEXA AB (SE) 2023-06-15 — — WO claimed
EP-3129909-A1 SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT Metabolon, Inc. (US) 2017-02-15 — — EP claimed
WO-2015157407-A1 SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT METABOLON, INC. (US) 2015-10-15 — — WO claimed
US-20120058979-A1 METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS ZALICUS INC. (US) 2012-03-08 — — US claimed
US-20120028910-A1 STORAGE-STABLE AQUEOUS OPHTHALMIC FORMULATIONS FOVEA PHARMACEUTICALS (FR) 2012-02-02 — — US claimed
US-8080553-B2 Methods and reagents for the treatment of immunoinflammatory disorders ZALICUS INC. (US) 2011-12-20 — — US claimed
EP-2301628-A1 Methods and reagents for the treatment of immunoinflammatory disorders Zalicus Inc. (US) 2011-03-30 — — EP claimed
EP-2070550-A1 Use of combinations comprising a corticosteroid and a pyrimidopyrimidine in the treatment of inflammatory diseases Combinatorx, Incorporated (US) 2009-06-17 — — EP claimed
US-20070010502-A1 Methods and reagents for the treatment of immunoinflammatory disorders COMBINATORX INC. (US) 2007-01-11 — — US claimed
WO-1997038015-A1 ARTIFICIAL ANTIBODIES TO CORTICOSTEROIDS PREPARED BY MOLECULAR IMPRINTING IGEN, INC. (US) 1997-10-16 — — WO claimed
US-4391803-A STEROID BLEND HEPAR INDUSTRIES (US) 1983-07-05 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070010502-A1 Methods and reagents for the treatment of immunoinflammatory disorders IL5, TPMT, TSLP SERPINA6 12/4885FNTA 1588/4885FNTB 2668/4885
US-20260148848-A1 BIOMARKERS FOR DIAGNOSIS AND TREATMENT OF ENDOCRINE HYPERTENSION, AND METHODS OF IDENTIFICATION THEREOF SHBG, HSD11B2, HSD11B1 SERPINA6 8/4885FNTA 271/4885FNTB 1281/4885
US-20120058979-A1 METHODS AND REAGENTS FOR THE TREATMENT OF IMMUNOINFLAMMATORY DISORDERS IL5, TPMT, TSLP SERPINA6 12/4885FNTA 1588/4885FNTB 2668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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