Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 6/20 | 0.80 |
| ▸ | FNTA | P49354 | 1/20 | 0.75 |
| ▸ | FNTB | P49356 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.72 |
| ▸ | LMNA | P02545 | 8/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.72 |
| ▸ | SHBG | P04278 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.72 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.67 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.67 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.67 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.67 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.67 |
| ▸ | THPO | P40225 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14382323 | 1.00 | SERPINA6 (0.80) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL141611 | 1.00 | SERPINA6 (0.80) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL141610 | 1.00 | SERPINA6 (0.80) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL20239320 | 1.00 | SERPINA6 (0.80) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL9073248 | 0.91 | SERPINA6 (0.79) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL8751542 | 0.90 | FNTA (0.81) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL668966 | 0.89 | SERPINA6 (1.00) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL15904593 | 0.89 | SERPINA6 (1.00) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL14525642 | 0.89 | SERPINA6 (1.00) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL15920543 | 0.89 | SERPINA6 (1.00) | SERPINA6FNTAFNTBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106537145-A | Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment | 麦特博隆股份有限公司 | 2017-03-22 | — | — | CN | claimed |
| CN-104619328-B | The condensed quinoline alkane glucocorticoid receptor modulator of heteroaryl -one | 科赛普特治疗学股份有限公司 | 2018-10-02 | — | — | CN | disclosed |
| CN-106537145-A | Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment | 麦特博隆股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| US-20140309398-A1 | OLIGOMER-CORTICOSTEROID CONJUGATES | NEKTAR THERAPEUTICS | 2014-10-16 | — | — | US | disclosed |
| US-8796248-B2 | Oligomer-corticosteroid conjugates | NEKTAR THERAPEUTICS (US) | 2014-08-05 | — | — | US | disclosed |
| US-8796248-B2 | Oligomer-corticosteroid conjugates | NEKTAR THERAPEUTICS (US) | 2014-08-05 | — | — | US | disclosed |
| CN-102659659-B | Heterocyclic compound having inhibitory activity on 11-beta-hydroxysteroid dehydrogenase type I | SHIONOGI & CO | 2014-07-23 | — | — | CN | disclosed |
| CN-102659659-A | Heterocyclic compound having inhibitory activity on 11-beta-hydroxysteroid dehydrogenase type I | SHIONOGI & CO | 2012-09-12 | — | — | CN | disclosed |
| US-20100286107-A1 | Oligomer-Corticosteroid Conjugates | NEKTAR THERAPEUTICS (US) | 2010-11-11 | — | — | US | disclosed |
| US-20100286107-A1 | Oligomer-Corticosteroid Conjugates | NEKTAR THERAPEUTICS (US) | 2010-11-11 | — | — | US | disclosed |
| WO-2009045539-A2 | OLIGOMER-CORTICOSTEROID CONJUGATES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2009-04-09 | — | — | WO | disclosed |
| CN-101312951-A | Heterocyclic compounds having 11 beta-hydroxysteroid dehydrogenase type I inhibitory activity | SHIONOGI & CO (JP) | 2008-11-26 | — | — | CN | disclosed |
| CN-101006052-A | Pyrrole derivatives as pharmaceutical agents | EXELIXIS INC (US) | 2007-07-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286107-A1 | Oligomer-Corticosteroid Conjugates | SERPINA6, NR3C2, NR3C1 | SERPINA6 1/4885FNTA 653/4885FNTB 1779/4885 |
| US-20140309398-A1 | OLIGOMER-CORTICOSTEROID CONJUGATES | SERPINA6, NR3C1, NR3C2 | SERPINA6 1/4885FNTA 659/4885FNTB 2159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.