Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928189 | 0.81 | ALDH1A1 (0.33) | NPSR1L3MBTL1ALOX15KMT2AALDH1A1 | |
| SCHEMBL8752023 | 0.81 | ALDH1A1 (0.41) | NPSR1L3MBTL1ALOX15KMT2AALDH1A1 | |
| SCHEMBL5928298 | 0.79 | NPSR1 (0.35) | NPSR1L3MBTL1ALOX15KMT2AALDH1A1 | |
| SCHEMBL8752043 | 0.79 | ALOX15 (0.51) | ALOX15KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL8752094 | 0.79 | KMT2A (0.40) | ALOX15KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL8752079 | 0.79 | ALOX15 (0.38) | L3MBTL1ALOX15KMT2AALDH1A1HPGD | |
| SCHEMBL4109091 | 0.77 | HASPIN (0.37) | NPSR1L3MBTL1ALOX15KMT2AALDH1A1 | |
| SCHEMBL719258 | 0.76 | RAB9A (0.41) | NPSR1L3MBTL1KMT2AALDH1A1HPGD | |
| SCHEMBL8751982 | 0.76 | NPC1 (0.31) | NPSR1ALOX15KMT2AALDH1A1HPGD | |
| SCHEMBL7630476 | 0.76 | SLC22A12 (0.33) | NPSR1L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684011-A | Pyrimidine derivatives useful as nematicides | ZENECA LIMITED (GB) | 1997-11-04 | — | — | US | disclosed |
| EP-0660827-B1 | HETEROCYCLIC COMPOUNDS WITH PARASITICAL ACTIVITY | ZENECA LTD (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0660827-A1 | HETEROCYCLIC COMPOUNDS WIHT PARASITICAL ACTIVITY. | ZENECA LTD (GB) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006777-A1 | HETEROCYCLIC COMPOUNDS WIHT PARASITICAL ACTIVITY | ZENECA LIMITED (GB) | 1994-03-31 | — | — | WO | disclosed |