SCHEMBL8752103

SCHEMBL8752103

Cc1ccc(N)c(S(=O)(=O)O)c1N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.38
CYP3A4 P08684 5/20 0.38
TDP1 Q9NUW8 5/20 0.38
HSD17B10 Q99714 3/20 0.38
CASP1 P29466 3/20 0.38
NT5E P21589 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 2/20 0.38
HPGD P15428 2/20 0.38
RECQL P46063 2/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38
CASP7 P55210 1/20 0.38
POLB P06746 2/20 0.37
CD44 P16070 1/20 0.37
MAPT P10636 3/20 0.36
TSHR P16473 5/20 0.35
RAB9A P51151 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11579509 0.85 ALDH1A1 (0.42) ALDH1A1CYP3A4TDP1HSD17B10CASP1
SCHEMBL7733315 0.83 ALDH1A1 (0.38) ALDH1A1CYP3A4TDP1HSD17B10CASP1
SCHEMBL4812407 0.83 ALDH1A1 (0.41) ALDH1A1CYP3A4TDP1HSD17B10CASP1
SCHEMBL9339093 0.83 SENP7 (0.43) ALDH1A1CYP3A4TDP1HSD17B10CASP1
SCHEMBL5181911 0.82 ALDH1A1 (0.41) ALDH1A1CYP3A4TDP1HSD17B10CASP1
SCHEMBL9211904 0.82 ALDH1A1 (0.38) ALDH1A1CYP3A4TDP1HSD17B10CASP1
SCHEMBL7554123 0.80 ALDH1A1 (0.40) ALDH1A1CYP3A4TDP1HSD17B10CASP1
SCHEMBL8164868 0.79 ALDH1A1 (0.46) ALDH1A1CYP3A4TDP1HSD17B10CASP1
SCHEMBL428171 0.78 TSHR (0.39) ALDH1A1CYP3A4TDP1HSD17B10CASP1
SCHEMBL8020509 0.77 ALDH1A1 (0.35) ALDH1A1CYP3A4TDP1HSD17B10CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0538785-B1 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AG (DE) 1997-04-09 EP disclosed
EP-0212264-B1 COLOURED WATER SOLUBLE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1989-05-31 EP disclosed
EP-0093369-B1 REACTIVE DYES BAYER AG (DE) 1986-07-23 EP disclosed
EP-0093369-A2 Reactive dyes BAYER AG (DE) 1983-11-09 EP disclosed
US-4268267-A PRINTING AND DYEING TEXTILES BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed