SCHEMBL428171

SCHEMBL428171

Cc1c(N)ccc(N)c1S(=O)(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
CYP3A4 P08684 3/20 0.39
PIK3CA P42336 1/20 0.39
ALDH1A1 P00352 8/20 0.38
NT5E P21589 2/20 0.38
HSD17B10 Q99714 6/20 0.36
KDM4E B2RXH2 4/20 0.36
GAA P10253 3/20 0.36
HPGD P15428 3/20 0.36
THRB P10828 2/20 0.36
CASP1 P29466 2/20 0.36
RECQL P46063 2/20 0.36
MEN1 O00255 1/20 0.36
MAPT P10636 1/20 0.36
PKM P14618 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
ALOX15 P16050 1/20 0.36
TTR P02766 1/20 0.35
TDP1 Q9NUW8 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7733315 0.87 ALDH1A1 (0.38) TSHRCYP3A4ALDH1A1NT5EHSD17B10
SCHEMBL9001549 0.87 TSHR (0.36) TSHRCYP3A4PIK3CAALDH1A1NT5E
SCHEMBL28054299 0.85 ALDH1A1 (0.46) TSHRCYP3A4ALDH1A1NT5EHSD17B10
SCHEMBL11810695 0.85 AURKA (0.42) TSHRCYP3A4ALDH1A1NT5EHSD17B10
SCHEMBL9232347 0.84 ALDH1A1 (0.44) TSHRCYP3A4PIK3CAALDH1A1NT5E
SCHEMBL4991882 0.84 ALDH1A1 (0.44) TSHRCYP3A4PIK3CAALDH1A1NT5E
SCHEMBL8164868 0.83 ALDH1A1 (0.46) TSHRCYP3A4ALDH1A1NT5EHSD17B10
SCHEMBL8772709 0.82 SENP2 (0.36) TSHRCYP3A4PIK3CAALDH1A1NT5E
SCHEMBL8772714 0.82 SENP2 (0.36) TSHRCYP3A4PIK3CAALDH1A1NT5E
SCHEMBL11605096 0.81 CA1 (0.41) TSHRCYP3A4ALDH1A1HSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10626392-B2 Particulate solid composite material for nucleic acid purification, containing magnetic nanoparticles AXAGARIUS GMBH & CO. KG (DE) 2020-04-21 US claimed
US-20180127742-A1 PARTICULATE SOLID COMPOSITE MATERIAL FOR NUCLEIC ACID PURIFICATION, CONTAINING MAGNETIC NANOPARTICLES AXAGARIUS GMBH & CO. KG (DE) 2018-05-10 US claimed
US-12630666-B2 Urethane resin composition, foamed urethane sheet, and synthetic leather DIC CORPORATION (JP) 2026-05-19 US disclosed
US-12606953-B2 Urethane resin aqueous dispersion, synthetic leather, and method for producing synthetic leather DIC CORPORATION (JP) 2026-04-21 US disclosed
EP-3712203-B1 FOAMED URETHANE SHEET AND SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2026-03-04 EP disclosed
US-12545760-B2 Urethane resin composition, film, and synthetic leather DIC CORPORATION (JP) 2026-02-10 US disclosed
US-12486439-B2 Urethane resin composition, adhesive, and synthetic leather DIC CORPORATION (JP) 2025-12-02 US disclosed
EP-4299830-B1 SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2025-10-29 EP disclosed
EP-3666101-B1 METHOD FOR MANUFACTURING GLOVES DAINIPPON INK & CHEMICALS (JP) 2025-10-15 EP disclosed
EP-3901365-B1 URETHANE RESIN COMPOSITION, FILM AND SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2025-10-15 EP disclosed
EP-4169961-B1 URETHANE RESIN COMPOSITION, FILM, AND SYNTHETIC LEATHER DAINIPPON INK & CHEMICALS (JP) 2025-10-08 EP disclosed
EP-1285936-A2 Polyurethane resin water dispersion and aqueous polyurethane adhesive MITSUI TAKEDA CHEMICALS, INC. (JP) 2003-02-26 EP disclosed
US-20020176968-A1 Inkjet recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2002-11-28 US disclosed
EP-1245402-A2 Inkjet recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2002-10-02 EP disclosed
CN-1366543-A Anthraquinone compound and aqueous ink for inkjet recording using the same MITSUI CHEMICALS INC (JP) 2002-08-28 CN disclosed
EP-1174477-A1 ANTHRAQUINONE COMPOUND AND WATER-BASED INK-JET RECORDING INK CONTAINING THE COMPOUND Mitsui Chemicals, Inc. (JP) 2002-01-23 EP disclosed
CN-1322227-A Yellow toner compound and aqueous ink for ink-jet recording apparatus using the same MITSUI CHEMICALS INC (JP) 2001-11-14 CN disclosed
EP-1125990-A1 YELLOW COMPOUND AND WATER-BASED INK-JET RECORDING INK CONTAINING THE COMPOUND Mitsui Chemicals, Inc. (JP) 2001-08-22 EP disclosed
CN-1281015-A Water containing printing ink for ink jet recording MITSUI CHEMICALS INC (JP) 2001-01-24 CN disclosed
EP-1055712-A2 Aqueous ink for ink jet recording Mitsui Chemicals, Inc. (JP) 2000-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545760-B2 Urethane resin composition, film, and synthetic leather PUF60, COL1A1, DEGS1 TSHR 4501/4885CYP3A4 3812/4885PIK3CA 1677/4885
US-12606953-B2 Urethane resin aqueous dispersion, synthetic leather, and method for producing synthetic leather PUF60, CUTA, UBA2 TSHR 4609/4885CYP3A4 3850/4885PIK3CA 2956/4885
US-12630666-B2 Urethane resin composition, foamed urethane sheet, and synthetic leather DEGS1, EBP, UTS2R TSHR 3853/4885CYP3A4 3122/4885PIK3CA 2010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.