SCHEMBL8752437

SCHEMBL8752437

COc1ccc(S(=O)(=O)Nc2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.78
PLAU P00749 4/20 0.77
LMNA P02545 2/20 0.69
GAA P10253 1/20 0.69
MAPK1 P28482 1/20 0.69
UQCRB P14927 2/20 0.65
CYP19A1 P11511 1/20 0.65
ALDH1A1 P00352 2/20 0.64
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
PKM P14618 2/20 0.63
KDM4E B2RXH2 1/20 0.63
MAPT P10636 1/20 0.63
BLM P54132 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
TSHR P16473 1/20 0.62
HTT P42858 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
KEAP1 Q14145 1/20 0.62
NFE2L2 Q16236 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32679643 0.94 GAA (0.78) PGRPLAULMNAGAAMAPK1
SCHEMBL29031235 0.92 PGR (0.85) PGRPLAULMNAGAAMAPK1
SCHEMBL4662975 0.90 PGR (0.82) PGRPLAULMNAGAAMAPK1
SCHEMBL812663 0.90 PGR (0.82) PGRPLAULMNAGAAMAPK1
SCHEMBL790294 0.88 GAA (0.86) PGRPLAULMNAGAAMAPK1
SCHEMBL10954094 0.86 PGR (0.75) PGRLMNAGAAMAPK1CYP19A1
SCHEMBL13028454 0.85 GFER (0.67) PGRPLAULMNAGAAMAPK1
SCHEMBL31681417 0.84 CYP19A1 (0.68) PGRPLAULMNACYP19A1ALDH1A1
SCHEMBL812677 0.83 KMT2A (0.77) PGRGAAMAPK1UQCRBALDH1A1
SCHEMBL13480185 0.83 KMT2A (0.77) PGRLMNAUQCRBALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP claimed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP disclosed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US disclosed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP disclosed