SCHEMBL32679643

SCHEMBL32679643

COc1ccc(NS(=O)(=O)c2ccc(-c3ccc(OC)cc3)cc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.78
MAPK1 P28482 2/20 0.78
LMNA P02545 2/20 0.78
PLAU P00749 3/20 0.77
ALDH1A1 P00352 6/20 0.71
PGR P06401 1/20 0.71
CYP19A1 P11511 1/20 0.68
PKM P14618 3/20 0.67
MAPT P10636 3/20 0.66
SMN1; SMN2 Q16637 3/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
KDM4E B2RXH2 1/20 0.66
BLM P54132 1/20 0.66
TDP1 Q9NUW8 1/20 0.66
GFER P55789 1/20 0.66
TSHR P16473 1/20 0.64
HTT P42858 1/20 0.64
KEAP1 Q14145 1/20 0.64
NFE2L2 Q16236 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL790294 0.94 GAA (0.86) GAAMAPK1LMNAPLAUALDH1A1
SCHEMBL8752437 0.94 PGR (0.78) GAAMAPK1LMNAPLAUALDH1A1
SCHEMBL13028454 0.88 GFER (0.67) GAAMAPK1LMNAPLAUALDH1A1
SCHEMBL28575423 0.88 KIF11 (0.65) GAAMAPK1LMNAPLAUALDH1A1
SCHEMBL7564170 0.88 GAA (0.76) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL806437 0.88 GAA (0.76) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL29031235 0.88 PGR (0.85) GAAMAPK1LMNAPLAUALDH1A1
SCHEMBL30434229 0.88 GAA (0.76) GAAMAPK1LMNAALDH1A1PGR
SCHEMBL95815 0.86 GAA (0.73) GAAMAPK1LMNAPLAUALDH1A1
SCHEMBL6301477 0.86 GAA (0.73) GAAMAPK1LMNAALDH1A1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121570445-A Use of N- (4-methoxyphenyl) -4- (4-methoxyphenyl) benzenesulfonamide in preparing medicament for treating allergic diseases 西安交通大学 2026-02-27 CN claimed
CN-121570445-A Use of N- (4-methoxyphenyl) -4- (4-methoxyphenyl) benzenesulfonamide in preparing medicament for treating allergic diseases 西安交通大学 2026-02-27 CN disclosed
CN-121570445-A Use of N- (4-methoxyphenyl) -4- (4-methoxyphenyl) benzenesulfonamide in preparing medicament for treating allergic diseases 西安交通大学 2026-02-27 CN disclosed
CN-121570445-A Use of N- (4-methoxyphenyl) -4- (4-methoxyphenyl) benzenesulfonamide in preparing medicament for treating allergic diseases 西安交通大学 2026-02-27 CN disclosed