Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133412 | 0.91 | HSD17B1 (0.45) | POLBPARP1CNR2HSD17B1HSD17B2 | |
| SCHEMBL13781004 | 0.89 | POLB (0.43) | POLBPARP1CNR2HSD17B1HSD17B2 | |
| SCHEMBL13781015 | 0.87 | LMNA (0.47) | POLBPARP1CNR2HSD17B1HSD17B2 | |
| SCHEMBL13780980 | 0.86 | TDP1 (0.47) | POLBCNR2HSD17B1HSD17B2TDP1 | |
| SCHEMBL13780986 | 0.83 | L3MBTL1 (0.53) | POLBCNR2TDP1HPGDATM | |
| SCHEMBL27828940 | 0.82 | L3MBTL1 (0.61) | TDP1HPGDATML3MBTL1CYP3A4 | |
| SCHEMBL9188288 | 0.82 | HSD17B1 (0.44) | PARP1HSD17B1HSD17B2TDP1HPGD | |
| SCHEMBL9853340 | 0.82 | DHODH (0.45) | POLBPARP1HSD17B1HSD17B2TDP1 | |
| SCHEMBL186545 | 0.82 | PARP1 (0.68) | POLBPARP1CNR2TDP1HPGD | |
| SCHEMBL29503529 | 0.82 | PARP1 (0.68) | POLBPARP1CNR2TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402462-A | Condensed ring compound, preparation method and application thereof, co-host material, light-emitting composition, light-emitting device, lighting device and display device | 中国石油化工股份有限公司 | 2021-09-17 | — | — | CN | disclosed |