Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 6/20 | 0.69 |
| ▸ | SHBG | P04278 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | BLM | P54132 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.67 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.63 |
| ▸ | HTR2B | P41595 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989808 | 1.00 | SERPINA6 (0.69) | SERPINA6SHBGLMNASMN1; SMN2BLM | |
| SCHEMBL10868078 | 0.88 | SERPINA6 (0.80) | SERPINA6SHBGLMNASMN1; SMN2BLM | |
| SCHEMBL9221947 | 0.88 | SERPINA6 (0.80) | SERPINA6SHBGLMNASMN1; SMN2BLM | |
| SCHEMBL8755727 | 0.88 | SERPINA6 (0.80) | SERPINA6SHBGLMNASMN1; SMN2BLM | |
| SCHEMBL9347240 | 0.85 | SHBG (0.70) | SERPINA6SHBGLMNASMN1; SMN2BLM | |
| SCHEMBL11207658 | 0.82 | SHBG (0.71) | SERPINA6SHBGLMNASMN1; SMN2BLM | |
| SCHEMBL14150039 | 0.81 | SHBG (0.77) | SERPINA6SHBGLMNASMN1; SMN2BLM | |
| SCHEMBL18891189 | 0.81 | SHBG (0.77) | SERPINA6SHBGLMNASMN1; SMN2BLM | |
| SCHEMBL18891198 | 0.81 | SHBG (0.77) | SERPINA6SHBGLMNASMN1; SMN2BLM | |
| SCHEMBL8093443 | 0.81 | SHBG (0.77) | SERPINA6SHBGLMNASMN1; SMN2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274118-B1 | INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE | NORDION INTERNATIONAL INC. (CA) | 2001-08-14 | — | — | US | disclosed |
| WO-1995002424-A1 | LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN | NORDION INTERNATIONAL INC. (CA) | 1995-01-26 | — | — | WO | disclosed |