Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTRA1 | Q92743 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759651 | 0.78 | KDM4E (0.38) | HTRA1KDM4EPKMKMT2AACE | |
| SCHEMBL9686556 | 0.78 | UCHL1 (0.44) | HTRA1KDM4EPKMKMT2AACE | |
| SCHEMBL8758593 | 0.77 | ECE1 (0.47) | HTRA1KDM4EPKMKMT2AACE | |
| SCHEMBL6947047 | 0.76 | KMT2A (0.41) | HTRA1KDM4EPKMKMT2AACE | |
| SCHEMBL6947045 | 0.76 | KMT2A (0.41) | HTRA1KDM4EPKMKMT2AACE | |
| SCHEMBL21640298 | 0.76 | KDM4E (0.49) | KDM4EPKMKMT2AGPR119USP30 | |
| SCHEMBL8759160 | 0.73 | CHRM2 (0.43) | PIK3CDNR1H2NR1H3 | |
| SCHEMBL6398075 | 0.72 | KDM4E (0.54) | KDM4EPKMKMT2AGPR119USP30 | |
| SCHEMBL7203728 | 0.72 | KDM4E (0.54) | KDM4EPKMKMT2AGPR119USP30 | |
| SCHEMBL27400480 | 0.69 | KDM4E (0.46) | KDM4EPKMKMT2AGPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774465-A1 | Penem derivatives and antimicrobial agents containing the same | SUNTORY LIMITED (JP) | 1997-05-21 | — | — | EP | disclosed |