Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759065 | 0.86 | TDP1 (0.38) | TDP1L3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL316600 | 0.82 | ALDH1A1 (0.46) | TDP1L3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1269642 | 0.81 | CHRNA7 (0.51) | L3MBTL1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL28340938 | 0.81 | ALDH1A1 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4 | |
| SCHEMBL10961584 | 0.81 | L3MBTL1 (0.47) | TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL1664388 | 0.81 | CA1 (0.40) | TDP1L3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL18868387 | 0.80 | ALDH1A1 (0.44) | TDP1L3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9315366 | 0.80 | ALDH1A1 (0.34) | TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL23727557 | 0.79 | CA1 (0.42) | TDP1L3MBTL1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4303930 | 0.79 | CA1 (0.42) | TDP1L3MBTL1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5326895-A | 3-(vinylbenzyloxy)propylsilane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-07-05 | — | — | US | claimed |
| EP-0494549-B1 | 3-(Vinylbenzyloxy)propylsilane compounds and their preparation | SHINETSU CHEMICAL CO (JP) | 1997-05-28 | — | — | EP | disclosed |
| US-5326895-A | 3-(vinylbenzyloxy)propylsilane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-07-05 | — | — | US | disclosed |
| EP-0494549-A1 | 3-(Vinylbenzyloxy)propylsilane compounds, their preparation and polymers thereof | Shin-Etsu Chemical Co., Ltd. (JP) | 1992-07-15 | — | — | EP | disclosed |