Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062874 | 0.84 | SLC6A4 (0.50) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8727070 | 0.81 | PTPN1 (0.55) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8727063 | 0.81 | PTPN1 (0.55) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8759440 | 0.80 | MAOA (0.47) | SLC6A4 | |
| SCHEMBL8636517 | 0.78 | SLC6A4 (0.50) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL8760210 | 0.78 | POLB (0.58) | — | |
| SCHEMBL8818957 | 0.77 | SLC6A4 (0.50) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8818952 | 0.77 | SLC6A4 (0.50) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8634784 | 0.75 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2SLC6A3 | |
| SCHEMBL8986924 | 0.75 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652884-B1 | PHOSPHONATED ARYLETHANOLAMINE COMPOUNDS WITH ANTI-HYPERGLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1997-05-28 | — | — | EP | disclosed |
| US-5519006-A | Phosphonated arylethanolamine compounds with anti-hyperglycemic and/or anti-obesity activity | SMITHKLINE BEECHAM PLC (GB) | 1996-05-21 | — | — | US | disclosed |
| EP-0652884-A1 | PHOSPHONATED ARYLETHANOLAMINE COMPOUNDS WITH ANTI-HYPERGLYCEMIC AND/OR ANTI-OBESITY ACTIVITY. | SMITHKLINE BEECHAM PLC (GB) | 1995-05-17 | — | — | EP | disclosed |
| WO-1994002493-A1 | PHOSPHONATED ARYLETHANOLAMINE COMPOUNDS WITH ANTI-HYPERGLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-02-03 | — | — | WO | disclosed |