Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200095 | 0.78 | UPP1 (0.60) | UPP1ALDH1A1 | |
| SCHEMBL8760090 | 0.76 | UPP1 (0.49) | UPP1ALDH1A1TSHR | |
| SCHEMBL8429654 | 0.76 | UPP1 (0.49) | UPP1ALDH1A1TSHR | |
| SCHEMBL8760250 | 0.74 | SIRT2 (0.47) | UPP1ALDH1A1 | |
| SCHEMBL8760742 | 0.69 | UPP1 (0.48) | UPP1ALDH1A1 | |
| SCHEMBL7219933 | 0.68 | UPP1 (0.59) | UPP1ALDH1A1 | |
| SCHEMBL9266049 | 0.68 | UPP1 (0.40) | UPP1ALDH1A1TSHRDAO | |
| SCHEMBL8426877 | 0.68 | UPP1 (0.40) | UPP1ALDH1A1 | |
| SCHEMBL8760255 | 0.68 | UPP1 (0.40) | UPP1 | |
| SCHEMBL5199239 | 0.67 | UPP1 (0.44) | UPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |