Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760090 | 0.89 | UPP1 (0.49) | UPP1 | |
| SCHEMBL7213426 | 0.89 | SIRT2 (0.40) | SIRT2SIRT1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2036799 | 0.87 | UPP1 (0.39) | UPP1SIRT1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8760223 | 0.86 | HTT (0.33) | UPP1PNP | |
| SCHEMBL8760861 | 0.85 | GAA (0.32) | UPP1PNP | |
| SCHEMBL8760934 | 0.84 | UPP1 (0.37) | UPP1MEN1KMT2ASMN1; SMN2RXFP1 | |
| SCHEMBL8760119 | 0.83 | DUT (0.43) | SIRT2SIRT1 | |
| SCHEMBL8760250 | 0.82 | SIRT2 (0.47) | UPP1SIRT2SIRT1SMN1; SMN2RXFP1 | |
| SCHEMBL8426877 | 0.78 | UPP1 (0.40) | UPP1SIRT2SIRT1MEN1KMT2A | |
| SCHEMBL9357336 | 0.78 | UPP1 (0.58) | UPP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | claimed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | claimed |
| JP-3284670-A | — | — | None | — | — | JP | disclosed |
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| JP-H03284670-A | PYRIMIDINE NUCLEOSIDE DERIVATIVE AND ANTIVIRAL AGENT WITH THE SAME AS ACTIVE INGREDIENT | MITSUBISHI KASEI CORP | 1991-12-16 | — | — | JP | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |