Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760114 | 0.90 | DUT (0.49) | DUTSIRT2SIRT1BUB1ALDH1A1 | |
| SCHEMBL9353904 | 0.82 | DUT (0.47) | DUTSIRT2SIRT1BUB1KDM4E | |
| SCHEMBL9353718 | 0.81 | DUT (0.47) | DUTSIRT2SIRT1BUB1ALDH1A1 | |
| SCHEMBL8760238 | 0.81 | UPP1 (0.37) | SIRT2SIRT1KDM4EALDH1A1MAPT | |
| SCHEMBL7213420 | 0.80 | SIRT2 (0.41) | SIRT2SIRT1KDM4EALDH1A1MAPT | |
| SCHEMBL9353918 | 0.77 | DUT (0.43) | DUTSIRT2SIRT1BUB1 | |
| SCHEMBL9357376 | 0.77 | DUT (0.51) | DUTKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8760119 | 0.76 | DUT (0.43) | DUTSIRT2SIRT1NPSR1 | |
| SCHEMBL8760122 | 0.73 | SIRT2 (0.34) | SIRT2SIRT1 | |
| SCHEMBL8760250 | 0.70 | SIRT2 (0.47) | SIRT2SIRT1ALDH1A1NPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |