Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760905 | 0.90 | DUT (0.47) | DUTTSHRMAPK1NPSR1DHFR | |
| SCHEMBL8760114 | 0.84 | DUT (0.49) | DUTSIRT2SIRT1NPSR1 | |
| SCHEMBL8760255 | 0.83 | UPP1 (0.40) | SIRT2SIRT1 | |
| SCHEMBL7213426 | 0.83 | SIRT2 (0.40) | SIRT2SIRT1TSHRMAPK1NPSR1 | |
| SCHEMBL9353908 | 0.79 | DUT (0.49) | DUTTSHRMAPK1NPSR1 | |
| SCHEMBL9353726 | 0.78 | DUT (0.48) | DUTTSHRMAPK1NPSR1 | |
| SCHEMBL8760109 | 0.76 | DUT (0.43) | DUTSIRT2SIRT1NPSR1 | |
| SCHEMBL9353904 | 0.75 | DUT (0.47) | DUTSIRT2SIRT1NPSR1 | |
| SCHEMBL9353718 | 0.75 | DUT (0.47) | DUTSIRT2SIRT1NPSR1 | |
| SCHEMBL9353922 | 0.74 | DUT (0.44) | DUTTSHRMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |