⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17348245 | 0.94 | — | — | |
| SCHEMBL2735132 | 0.84 | — | — | |
| SCHEMBL22404285 | 0.84 | ADH1A (0.32) | — | |
| SCHEMBL12658452 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL20273253 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL23543234 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL8290254 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL8043535 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL15892155 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL23104995 | 0.80 | ADH1C (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775259-B | Amatinib intermediate Synthesis method of intermediate | 烟台舜康生物科技有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-119775259-A | Amatinib intermediate Synthesis method of intermediate | 烟台舜康生物科技有限公司 | 2025-04-08 | — | — | CN | claimed |
| US-20250163077-A1 | MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE (PKMYT1) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (HK) | 2025-05-22 | — | — | US | disclosed |
| CN-119775259-B | Amatinib intermediate Synthesis method of intermediate | 烟台舜康生物科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-119775259-A | Amatinib intermediate Synthesis method of intermediate | 烟台舜康生物科技有限公司 | 2025-04-08 | — | — | CN | disclosed |
| US-20240226106-A1 | INHIBITORS OF PLASMA KALLIKREIN | SHIRE HUMAN GENETIC THERAPIES (US) | 2024-07-11 | — | — | US | disclosed |
| WO-2024141757-A1 | LSD1 MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2024-07-04 | — | — | WO | disclosed |
| CN-117886805-A | FabI enzyme inhibitor and preparation method and application thereof | 广州白云山医药集团股份有限公司白云山制药总厂 | 2024-04-16 | — | — | CN | disclosed |
| EP-3712144-B1 | P2X3 AND/OR P2X2/3 RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO LTD (CN) | 2024-02-14 | — | — | EP | disclosed |
| US-20240025882-A1 | BENZAMIDES OF PYRAZOLYLAMINO- PYRIMIDINYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2024-01-25 | — | — | US | disclosed |
| EP-4301752-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Cambridge Enterprise Limited (GB) | 2024-01-10 | — | — | EP | disclosed |
| US-7410998-B2 | Inhibitors of NADH:ubiquinone oxidoreductase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-08-12 | — | — | US | disclosed |
| WO-2008080120-A2 | 3-AMINO CHROMANE DERIVATIVES | WYETH (US) | 2008-07-03 | — | — | WO | disclosed |
| US-7390825-B1 | Process for the preparation of oxazolidinones and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-24 | — | — | US | disclosed |
| US-20080146458-A1 | PROCESS FOR THE PREPARATION OF OXAZOLIDINONES AND METHOD OF USE THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-06-19 | — | — | US | disclosed |
| US-7354656-B2 | Floor covering made from an environmentally friendly polylactide-based composite formulation | MICHIGAN STATE UNIVERSITY, BOARD OF TRUSTEES (US) | 2008-04-08 | — | — | US | disclosed |
| US-20070257023-A1 | Heater plate and a method for manufacturing the heater plate | WATANABE KATSUMI | 2007-11-08 | — | — | US | disclosed |
| WO-2007056497-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007025144-A1 | 5-HT2C RECEPTOR AGONISTS AS ANORECTIC AGENTS | UNIVERSITY OF ILLINOIS - CHICAGO (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2004078733-A1 | QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2004-09-16 | — | — | WO | disclosed |