Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8760208 | 0.99 | OPRK1 (0.38) | OPRK1ALOX5GAAKMT2A | |
| SCHEMBL8946090 | 0.88 | ALOX5 (0.39) | OPRK1ALOX5KMT2A | |
| SCHEMBL8946088 | 0.87 | ALOX5 (0.41) | OPRK1ALOX5KMT2A | |
| SCHEMBL8761049 | 0.86 | ALOX5 (0.36) | ALOX5KMT2A | |
| SCHEMBL8761051 | 0.84 | GAA (0.42) | ALOX5GAA | |
| SCHEMBL8945876 | 0.82 | ALOX5 (0.35) | ALOX5KMT2A | |
| Maleic Acid SCHEMBL8761537 | 0.81 | ALOX5 (0.33) | OPRK1ALOX5GAAKMT2A | |
| Fumaric Acid SCHEMBL8761550 | 0.81 | ALOX5 (0.33) | OPRK1ALOX5GAAKMT2A | |
| SCHEMBL8945840 | 0.80 | ALOX5 (0.35) | ALOX5KMT2A | |
| SCHEMBL8761014 | 0.75 | MAPK8 (0.36) | ALOX5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557305-B1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES | ASTRA AB (SE) | 1997-06-11 | — | — | EP | claimed |
| EP-0557305-A1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES. | FISONS CORP (US) | 1993-09-01 | — | — | EP | claimed |
| WO-1992005169-A1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1992-04-02 | — | — | WO | claimed |