Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760050 | 0.89 | UPP1 (0.35) | PNPHTT | |
| SCHEMBL8760934 | 0.86 | UPP1 (0.37) | PNPTSHR | |
| SCHEMBL8760223 | 0.84 | HTT (0.33) | PNPHTT | |
| SCHEMBL8430830 | 0.79 | PNP (0.33) | PNPHTTUSP2TSHREDNRA | |
| SCHEMBL8760732 | 0.75 | UPP1 (0.46) | PNPTSHR | |
| SCHEMBL2036799 | 0.74 | UPP1 (0.39) | PNPHTTTSHR | |
| SCHEMBL8760930 | 0.73 | UPP1 (0.38) | HTT | |
| SCHEMBL8760861 | 0.73 | GAA (0.32) | PNPHTT | |
| SCHEMBL9016475 | 0.72 | KDM4E (0.32) | PNPHTT | |
| SCHEMBL8760939 | 0.72 | UPP1 (0.39) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | claimed |
| EP-0449726-B1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | MITSUBISHI CHEM CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5318972-A | Active against retroviruses, human t-cell leukemia/lymphoma viruses | MITSUBISHI KASEI CORPORATION (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0449726-A1 | Pyrimidine nucleoside derivative and antiviral agent containing the derivative as active ingredient | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |