Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9482785 | 0.98 | SLC6A2 (0.44) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Fumaric Acid SCHEMBL9482738 | 0.89 | SLC15A1 (0.46) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| Maleic Acid SCHEMBL9482727 | 0.89 | SLC15A1 (0.46) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL9425163 | 0.79 | ALOX5 (0.35) | — | |
| Hydrochloric Acid SCHEMBL8945783 | 0.78 | CYP3A4 (0.36) | — | |
| SCHEMBL8760252 | 0.77 | TAAR1 (0.44) | SLC6A2TAAR1MAOASLC6A4SLC6A3 | |
| SCHEMBL8862666 | 0.76 | GRIN2D (0.54) | — | |
| SCHEMBL12261609 | 0.76 | ALOX5 (0.42) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL9482849 | 0.76 | TAAR1 (0.43) | TAAR1SIGMAR1CYP2D6 | |
| SCHEMBL8761523 | 0.74 | SIGMAR1 (0.47) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557305-B1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES | ASTRA AB (SE) | 1997-06-11 | — | — | EP | disclosed |
| EP-0557305-A1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES. | FISONS CORP (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5109017-A | (2-thienyl)alkylamine derivatives having neuroprotective properties | FISONS CORPORATION (US) | 1992-04-28 | — | — | US | disclosed |
| WO-1992005169-A1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |