Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761001 | 0.88 | MEN1 (0.41) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8761011 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10572912 | 0.78 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9583533 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL9482717 | 0.74 | SIGMAR1 (0.46) | — | |
| SCHEMBL9425074 | 0.73 | MAPT (0.39) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9425330 | 0.72 | L3MBTL1 (0.38) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8761197 | 0.72 | KMT2A (0.37) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8945759 | 0.71 | L3MBTL1 (0.37) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9425664 | 0.70 | MAPK1 (0.41) | ALDH1A1MEN1KMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557305-B1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES | ASTRA AB (SE) | 1997-06-11 | — | — | EP | disclosed |
| EP-0557305-A1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES. | FISONS CORP (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992005169-A1 | (2-THIENYL) ALKYLAMINE DERIVATIVES HAVING NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |