Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.67 |
| ▸ | SNCA | P37840 | 4/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | BLM | P54132 | 3/20 | 0.67 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.62 |
| ▸ | PGR | P06401 | 6/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.60 |
| ▸ | AR | P10275 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760343 | 1.00 | SHBG (0.67) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL930380 | 0.81 | SMN1; SMN2 (0.73) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL930379 | 0.81 | SMN1; SMN2 (0.73) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 | |
| Androstenedione SCHEMBL13753017 | 0.81 | CYP19A1 (1.00) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 | |
| Androstenedione SCHEMBL9310209 | 0.81 | CYP19A1 (1.00) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 | |
| Androstenedione SCHEMBL11876371 | 0.81 | CYP19A1 (1.00) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 | |
| Androstenedione SCHEMBL12367193 | 0.81 | CYP19A1 (1.00) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 | |
| Androstenedione SCHEMBL12153462 | 0.81 | CYP19A1 (1.00) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 | |
| Androstenedione SCHEMBL13752932 | 0.81 | CYP19A1 (1.00) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 | |
| Androstenedione SCHEMBL21265627 | 0.81 | CYP19A1 (1.00) | SHBGLMNASMN1; SMN2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582713-B1 | -New D-homo-17-oxa and D-homo-17-aza-androstane derivatives | TEIKOKU HORMONE MFG CO LTD (JP) | 1997-06-04 | — | — | EP | disclosed |
| US-5519051-A | AROMATASE INHIBITORS USEFUL FOR TREATMENT OF DISEASES CAUSED BY EXCESS OF ESTROGEN, FOR EXAMPLE, BREAST CANCER, UTERINE CANCER | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0582713-A1 | NOVEL OXA- OR AZASTEROID DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1994-02-16 | — | — | EP | disclosed |