Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760496 | 1.00 | LMNA (0.44) | LMNARNPEPCTSSCTSKUSP2 | |
| SCHEMBL2106791 | 0.85 | RNPEP (0.47) | LMNARNPEPCTSSCTSKUSP2 | |
| SCHEMBL14383421 | 0.85 | RNPEP (0.47) | LMNARNPEPCTSSCTSKUSP2 | |
| SCHEMBL2106793 | 0.85 | RNPEP (0.47) | LMNARNPEPCTSSCTSKUSP2 | |
| Hydrochloric Acid SCHEMBL8602262 | 0.84 | RNPEP (0.46) | LMNARNPEPCTSSCTSKUSP2 | |
| Hydrochloric Acid SCHEMBL8602261 | 0.84 | RNPEP (0.46) | LMNARNPEPCTSSCTSKUSP2 | |
| SCHEMBL4430146 | 0.80 | RNPEP (0.46) | LMNARNPEPUSP2TSHRALDH1A1 | |
| SCHEMBL4430147 | 0.80 | RNPEP (0.46) | LMNARNPEPUSP2TSHRALDH1A1 | |
| Acrylic Acid SCHEMBL1878744 | 0.77 | ALDH1A1 (0.41) | LMNARNPEPCTSSCTSKUSP2 | |
| SCHEMBL29456085 | 0.77 | RNPEP (0.54) | LMNARNPEPUSP2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672745-A | HYDROLYSIS OF METHONINE NITRILE TO METHONINE OR SALTS IN PRESENCE OF KETONE, FOLLOWED BY SAPONIFICATION WITH BASE TO FORM CRUDE METHIONINE PDRODUCT MIXTURE, AND SIMULTANEOUS DRAWING OF AMMONIA, KETONE AND WATER | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1997-09-30 | — | — | US | disclosed |
| EP-0665832-B1 | METHOD FOR THE CONTINUOUS PREPARATION OF METHIONINE OR METHIONINE DERIVATIVES | DEGUSSA (DE) | 1997-04-16 | — | — | EP | disclosed |