SCHEMBL8760540

SCHEMBL8760540

N#CCC(=C(C#N)C#N)c1ccc(C(=O)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 3/20 0.46
TSHR P16473 3/20 0.44
TP53 P04637 1/20 0.44
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
SRD5A2 P31213 2/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA12 O43570 1/20 0.39
CA3 P07451 1/20 0.39
TYR P14679 1/20 0.39
DRD1 P21728 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA5A P35218 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1930563 0.82 CYP19A1 (0.58) CYP19A1CES2CES1ALDH1A1SMN1; SMN2
SCHEMBL14918493 0.76 TSHR (0.52) TSHRTP53CES2CES1SRD5A2
SCHEMBL28342288 0.74 TSHR (0.55) TSHRTP53CES2CES1SRD5A2
Terephthalic Acid SCHEMBL27624424 0.73 TSHR (0.60) TSHRTP53CES2CES1SRD5A2
SCHEMBL8075056 0.73 PTGS2 (0.49) TSHRCA1CA2CA12CA9
Benzoic Acid SCHEMBL23361728 0.71 TSHR (0.58) CYP19A1TSHRTP53CES2CES1
SCHEMBL28166370 0.70 ALDH1A1 (0.47) TSHRTP53CES2CES1SRD5A2
Terephthalic Acid SCHEMBL5014892 0.69 TSHR (0.92) TSHRTP53CES2CES1SRD5A2
Terephthalic Acid SCHEMBL31011418 0.69 TSHR (0.92) TSHRTP53CES2CES1SRD5A2
Terephthalic Acid SCHEMBL11771938 0.69 TSHR (0.92) TSHRTP53CES2CES1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524598-B1 Solid particle dispersions of filter dyes for photographic elements EASTMAN KODAK CO (US) 1997-06-11 EP disclosed
US-5399690-A Contain at least two nitrile groups, non-wandering EASTMAN KODAK COMPANY (US) 1995-03-21 US disclosed
US-5213956-A Cyano-vinyl filter dye EASTMAN KODAK COMPANY (US) 1993-05-25 US disclosed
EP-0524598-A1 Solid particle dispersions of filter dyes for photographic elements EASTMAN KODAK COMPANY (US) 1993-01-27 EP disclosed