SCHEMBL1930563

SCHEMBL1930563

N#CCC(=C(C#N)C#N)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.58
ALDH1A1 P00352 4/20 0.44
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
MCL1 Q07820 1/20 0.38
MAPT P10636 4/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
POLB P06746 2/20 0.35
HPGD P15428 2/20 0.34
PTGS2 P35354 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8760540 0.82 CYP19A1 (0.46) CYP19A1ALDH1A1CES2CES1SMN1; SMN2
SCHEMBL4415163 0.79 ALDH1A1 (0.44) CYP19A1ALDH1A1MEN1KMT2AMAPT
SCHEMBL6117869 0.79 ESR1 (0.48) CYP19A1ALDH1A1MEN1KMT2AMAPT
SCHEMBL14362835 0.79 ALDH1A1 (0.44) CYP19A1ALDH1A1MEN1KMT2AMAPT
SCHEMBL16550069 0.78 ALDH1A1 (0.43) CYP19A1ALDH1A1MEN1KMT2AMAPT
SCHEMBL29227309 0.75 KEAP1 (0.44) CYP19A1ALDH1A1MAPTKDM4EPOLB
SCHEMBL18863034 0.73 CYP19A1 (1.00) CYP19A1CES2PTGS2
SCHEMBL4478277 0.72 HDAC3 (0.49) ALDH1A1MAPTLMNAPTGS2CYP2C19
SCHEMBL28642591 0.71 L3MBTL1 (0.41) CYP19A1ALDH1A1MEN1KMT2AMAPT
SCHEMBL13172497 0.71 ALDH1A1 (0.38) CYP19A1ALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775938-B1 Combination of yellow filter dye and 4-equivalent pyrazolone magenta coupler EASTMAN KODAK CO (US) 2003-02-12 EP claimed
US-5834172-A A COATING COMPRISING AN AQUEOUS HYDROPHILIC COLLOID HAVING A DISPERSION OF PARTICLES OF A YELLOW FILTER DYE AND ALSO AN OXIDIZED DEVELOPER HYDRAZIDE-CONTAINING SCAVENGER; CRYSTAL GROWTH INHIBITORS EASTMAN KODAK COMPANY (US) 1998-11-10 US claimed
US-5695917-A PREVENTS FORMATION OF YELLOW STAINING EASTMAN KODAK COMPANY (US) 1997-12-09 US claimed
EP-0775938-A1 Combination of yellow filter dye and 4-equivalent pyrazolone magenta coupler EASTMAN KODAK COMPANY (US) 1997-05-28 EP claimed
JP-9171230-A None JP disclosed
US-7955775-B2 Image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2011-06-07 US disclosed
US-20100046344-A1 OPTICAL RECORDING MEDIUM AND METHOD OF RECORDING VISIBLE INFORMATION FUJIFILM CORPORATION (JP) 2010-02-25 US disclosed
EP-1542221-B1 High speed Optical recording medium FUJIFILM CORP (JP) 2010-02-10 EP disclosed
EP-2111999-A1 OPTICAL RECORDING MEDIUM, AND VISIBLE INFORMATION RECORDING METHOD Fujifilm Corporation (JP) 2009-10-28 EP disclosed
US-20090130366-A1 Optical Information-Recording Medium and Information-Recording Method FUJIFILM CORPORATION (JP) 2009-05-21 US disclosed
US-7534546-B2 Image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2009-05-19 US disclosed
EP-1424691-B1 Optical information-recording medium, novel oxonol compound and method of recording information FUJIFILM CORP (JP) 2009-02-25 EP disclosed
US-5126312-A Storage stability; high image density EASTMAN KODAK COMPANY (US) 1992-06-30 US disclosed
US-5126313-A Storage stability; high density images EASTMAN KODAK COMPANY (US) 1992-06-30 US disclosed
US-5126314-A Storage stability; high density images EASTMAN KODAK COMPANY (US) 1992-06-30 US disclosed
US-5126311-A Storage stability; high density images EASTMAN KODAK COMPANY (US) 1992-06-30 US disclosed
EP-0483876-A1 Mixture of dyes for black dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1992-05-06 EP disclosed
EP-0483791-A1 Cyan azamethine dye-donor element for thermal dye transfer EASTMAN KODAK COMPANY (US) 1992-05-06 EP disclosed
EP-0483793-A1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1992-05-06 EP disclosed
US-5024990-A Accuracy EASTMAN KODAK COMPANY (US) 1991-06-18 US disclosed