Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | UNG | P13051 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4881018 | 0.84 | PPARA (0.46) | PTPN1UNGCA12CA1CA2 | |
| SCHEMBL8223753 | 0.81 | KMT2A (0.41) | PTPN1UNGCA12CA1CA2 | |
| SCHEMBL611180 | 0.80 | PTPN1 (0.45) | PTPN1HPGDTSHRALDH1A1KMT2A | |
| SCHEMBL6153204 | 0.80 | PTPN1 (0.49) | PTPN1HPGDTSHRALDH1A1KMT2A | |
| SCHEMBL10694157 | 0.80 | CHKA (0.41) | PTPN1ALDH1A1 | |
| SCHEMBL14898280 | 0.79 | LMNA (0.49) | PTPN1HPGDALDH1A1LMNAKMT2A | |
| SCHEMBL250420 | 0.79 | TSHR (0.46) | PTPN1CA12CA1CA2CA6 | |
| SCHEMBL6445977 | 0.78 | KMT2A (0.47) | PTPN1HPGDTSHRALDH1A1KMT2A | |
| SCHEMBL11215796 | 0.78 | KCNK3 (0.58) | HPGDALDH1A1KMT2A | |
| SCHEMBL872529 | 0.77 | ALDH1A1 (0.56) | CA12CA1CA2CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10059900-B2 | Aminobenzoic acid derivatives | THE LUBRIZOL CORPORATION (US) | 2018-08-28 | — | — | US | disclosed |
| US-20180002629-A1 | AMINOBENZOIC ACID DERIVATIVES | LUBRIZOL CORP (US) | 2018-01-04 | — | — | US | disclosed |
| US-9222051-B2 | Lubricating composition with improved TBN retention | THE LUBRIZOL CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| US-20140187458-A1 | Lubricating Composition With Improved TBN Retention | THE LUBRIZOL CORPORATION (US) | 2014-07-03 | — | — | US | disclosed |
| US-20130281336-A1 | Aminobenzoic Acid Derivatives | THE LUBRIZOL CORPORATION (US) | 2013-10-24 | — | — | US | disclosed |
| EP-2619293-A1 | AMINOBENZOIC ACID DERIVATIVES | The Lubrizol Corporation (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012166781-A1 | LUBRICATING COMPOSITION WITH IMPROVED TBN RETENTION | THE LUBRIZOL CORPORATION (US) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012040021-A1 | AMINOBENZOIC ACID DERIVATIVES | THE LUBRIZOL CORPORATION (US) | 2012-03-29 | — | — | WO | disclosed |