Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687016 | 0.87 | TSHR (0.62) | ALDH1A1KMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL10689801 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP3A4KMT2AHCAR3POLB | |
| SCHEMBL2742811 | 0.87 | ALDH1A1 (0.58) | ALDH1A1CYP3A4KMT2AMEN1L3MBTL1 | |
| SCHEMBL610585 | 0.86 | L3MBTL1 (0.57) | ALDH1A1CYP3A4KMT2AMEN1L3MBTL1 | |
| SCHEMBL872723 | 0.86 | HCAR3 (0.49) | ALDH1A1KMT2ACA12CA1CA2 | |
| SCHEMBL11739758 | 0.85 | MAPT (0.63) | ALDH1A1CYP3A4KMT2AMEN1L3MBTL1 | |
| SCHEMBL11809714 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP3A4KMT2AMEN1L3MBTL1 | |
| Benzoic Acid SCHEMBL28813195 | 0.85 | ALDH1A1 (0.72) | ALDH1A1CYP3A4KMT2AMEN1L3MBTL1 | |
| SCHEMBL11581341 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4KMT2AMEN1L3MBTL1 | |
| SCHEMBL3107249 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | claimed |
| EP-1167540-B1 | Dye couple for spectrophotometric determination of analytes | LIFESCAN INC (US) | 2007-06-20 | — | — | EP | claimed |
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | disclosed |
| CN-103703114-B | There is the lubricating composition improving tbn retention | THE LUBRIZOL CORP. (US) | 2016-02-10 | — | — | CN | disclosed |
| US-9222051-B2 | Lubricating composition with improved TBN retention | THE LUBRIZOL CORPORATION (US) | 2015-12-29 | — | — | US | disclosed |
| CN-103210069-B | Aminobenzoic acid derivatives | THE LUBRIZOL CORP. (US) | 2015-11-25 | — | — | CN | disclosed |
| US-20140187458-A1 | Lubricating Composition With Improved TBN Retention | THE LUBRIZOL CORPORATION (US) | 2014-07-03 | — | — | US | disclosed |
| CN-103703114-A | Lubricating composition with improved tbn retention | LUBRIZOL CORP | 2014-04-02 | — | — | CN | disclosed |
| US-20130281336-A1 | Aminobenzoic Acid Derivatives | THE LUBRIZOL CORPORATION (US) | 2013-10-24 | — | — | US | disclosed |
| EP-2619293-A1 | AMINOBENZOIC ACID DERIVATIVES | The Lubrizol Corporation (US) | 2013-07-31 | — | — | EP | disclosed |
| CN-103210069-A | Aminobenzoic acid derivatives | LUBRIZOL CORP | 2013-07-17 | — | — | CN | disclosed |
| EP-0127203-B1 | NEW PHTHALIDE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND RECORDING SYSTEM UTILIZING THE SAME AS COLOURLESS CHROMOGENIC MATERIAL | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1989-06-28 | — | — | EP | disclosed |
| EP-0305093-A1 | Imidazo(1,2-b)pyridazine derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-03-01 | — | — | EP | disclosed |
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |
| US-4528136-A | Process for preparing 2-[bis(aryl)methyl]benzoic acids | THE HILTON-DAVIS CHEMICAL CO. (US) | 1985-07-09 | — | — | US | disclosed |
| US-4399291-A | CONDENSATION OF A BENZALDEHYDE, AN ANILINE, AN AMINOBENZOIC ACID; OXIDATION | STERLING DRUG INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0082394-A2 | A process for the production of aminophthalides and amino benzoic acids | STERLING DRUG INC. (US) | 1983-06-29 | — | — | EP | disclosed |
| EP-0014031-A1 | Water-soluble monoazo dyes of the azobenzene series, their preparation and process for the colouration of polyamide textile materials | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-08-06 | — | — | EP | disclosed |
| US-3936462-A | CNS DEPRESSANT, ANALGESIC | STERLING DRUG INC. (US) | 1976-02-03 | — | — | US | disclosed |