SCHEMBL8760864

SCHEMBL8760864

CO[Si](CCCNCCN=Cc1ccccc1)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.38
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
DRD3 P35462 1/20 0.37
SHBG P04278 1/20 0.36
CHRM2 P08172 11/20 0.34
GRIN1 Q05586 4/20 0.34
GRIN2A Q12879 4/20 0.34
BCHE P06276 4/20 0.34
ACHE P22303 4/20 0.34
CHRM4 P08173 3/20 0.34
CHRM5 P08912 3/20 0.34
CHRM1 P11229 3/20 0.34
CHRM3 P20309 3/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
THPO P40225 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2861242 0.86 CA2 (0.42) CA2SHBGTAAR1CA12CA1
SCHEMBL23526498 0.86 CA2 (0.42) CA2SHBGTAAR1CA12CA1
SCHEMBL2861245 0.86 CA2 (0.42) CA2SHBGTAAR1CA12CA1
SCHEMBL8760736 0.86 ALDH1A1 (0.34) CA2CA12CA1CA9
Dimethylamine SCHEMBL3840271 0.85 CA2 (0.40) CA2SHBGTP53TAAR1CA12
SCHEMBL10592839 0.79 CA2 (0.53) CA2GRIN1GRIN2ATAAR1CA12
SCHEMBL10592837 0.79 CA2 (0.53) CA2GRIN1GRIN2ATAAR1CA12
SCHEMBL5684934 0.78 ALDH1A1 (0.44) CA2SHBGGRIN1GRIN2ATAAR1
SCHEMBL20960343 0.78 ALDH1A1 (0.44) CA2SHBGGRIN1GRIN2ATAAR1
SCHEMBL5684928 0.78 ALDH1A1 (0.44) CA2SHBGGRIN1GRIN2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5698725-A IMINE-CONTAINING ORGANOSILICON COMPOUND DOW CORNING TORAY SILICONE CO., LTD. (JP) 1997-12-16 US disclosed
EP-0768313-A2 A surface treating agent for glass fiber substrates Dow Corning Toray Silicone Company Limited (JP) 1997-04-16 EP disclosed