SCHEMBL2861242

SCHEMBL2861242

CO[Si](CCC/N=C\c1ccccc1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.42
SHBG P04278 1/20 0.40
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 1/20 0.39
TAAR1 Q96RJ0 1/20 0.38
CA12 O43570 6/20 0.37
CA9 Q16790 5/20 0.37
CA1 P00915 1/20 0.37
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 2/20 0.35
G6PC1 P35575 1/20 0.35
POLB P06746 1/20 0.35
TRPA1 O75762 1/20 0.34
MEN1 O00255 1/20 0.34
HPGD P15428 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23526498 1.00 CA2 (0.42) CA2SHBGALDH1A1KDM4ETAAR1
SCHEMBL2861245 1.00 CA2 (0.42) CA2SHBGALDH1A1KDM4ETAAR1
Dimethylamine SCHEMBL3840271 0.95 CA2 (0.40) CA2SHBGALDH1A1KDM4ETAAR1
SCHEMBL5684928 0.91 ALDH1A1 (0.44) CA2SHBGALDH1A1KDM4ETAAR1
SCHEMBL5684934 0.91 ALDH1A1 (0.44) CA2SHBGALDH1A1KDM4ETAAR1
SCHEMBL20960343 0.91 ALDH1A1 (0.44) CA2SHBGALDH1A1KDM4ETAAR1
SCHEMBL8760864 0.86 CA2 (0.38) CA2SHBGTAAR1CA12CA9
SCHEMBL1259701 0.85 CA2 (0.41) CA2SHBGALDH1A1KDM4ETAAR1
SCHEMBL12250807 0.85 CA2 (0.41) CA2SHBGALDH1A1KDM4ETAAR1
SCHEMBL1259700 0.85 CA2 (0.41) CA2SHBGALDH1A1KDM4ETAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799391-B2 Liquid crystal composition, color filter and liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2010-09-21 US disclosed
US-7704571-B2 Liquid crystal composition, color filter and liquid crystal display apparatus, and method of forming phase difference layer DAI NIPPON PRINTING CO., LTD. (JP) 2010-04-27 US disclosed
US-20090195734-A1 Liquid Crystal Composition, Color Filter and Liquid Crystal Display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-06 US disclosed
US-20080303985-A1 Liquid Crystal Composition, Color Filter and Liquid Crystal Display Apparatus, and Method of Forming Phase Difference Layer DAI NIPPON PRINTING CO., LTD (JP) 2008-12-11 US disclosed
EP-1451198-B1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES,IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES GEN ELECTRIC (US) 2006-03-01 EP disclosed
US-6998499-B2 Process for the preparation of secondary and tertiary amino-functional silanes, iminoorganosilanes and/or imidoorganosilanes GENERAL ELECTRIC COMPANY (US) 2006-02-14 US disclosed
US-20030220513-A1 Process for the preparation of secondary and tertiary amino-functional silanes, iminoorganosilanes and/or imidoorganosilanes CROMPTON CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2003-11-27 US disclosed
US-6586612-B2 Reacting N-benzylidene aniline with 3-aminopropyltrimethoxy-silane to from N-benzylidene aminopropyltrimethoxysilane used as adhesion promoters in adhesives and sealants or couplers for plastics and glass fibers CROMPTON CORPORATION 2003-07-01 US disclosed
US-20030097014-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES, IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. 2003-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030097014-A1 PROCESS FOR THE PREPARATION OF SECONDARY AND TERTIARY AMINO-FUNCTIONAL SILANES, IMINOORGANOSILANES AND/OR IMIDOORGANOSILANES INMT, SI, DAO CA2 3477/4885SHBG 1527/4885ALDH1A1 805/4885
US-20030220513-A1 Process for the preparation of secondary and tertiary amino-functional silanes, iminoorganosilanes and/or imidoorganosilanes INMT, SI, DAO CA2 3477/4885SHBG 1527/4885ALDH1A1 805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.