Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.43 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761425 | 0.88 | TRIM24 (0.57) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL8415236 | 0.83 | ERN1 (0.62) | ERN1ALDH1A1LTA4HMAPT | |
| SCHEMBL31166228 | 0.83 | ERN1 (0.62) | ERN1LTA4H | |
| SCHEMBL902107 | 0.82 | KDM4E (0.49) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL8421788 | 0.81 | ERN1 (0.65) | ERN1 | |
| SCHEMBL8761203 | 0.81 | CA2 (0.49) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL9293338 | 0.81 | CA2 (0.49) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL29952821 | 0.79 | ERN1 (0.66) | ERN1KDM4EALDH1A1LTA4HMAPT | |
| SCHEMBL5882874 | 0.79 | ERN1 (0.66) | ERN1KDM4EALDH1A1LTA4HMAPT | |
| SCHEMBL7595046 | 0.79 | ERN1 (0.57) | ERN1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0521787-B1 | Vanadium complexes, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1997-04-23 | — | — | EP | disclosed |
| US-5278154-A | New vanadium complexes | ADIR ET COMPAGNIE (FR) | 1994-01-11 | — | — | US | disclosed |
| US-5266565-A | Antidiabetic | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |
| EP-0521787-A1 | Vanadium complexes, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-01-07 | — | — | EP | disclosed |