Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761203 | 0.96 | CA2 (0.49) | CA2CHRNB2CHRNA4KDM4EALDH1A1 | |
| SCHEMBL8761193 | 0.90 | CHRNB2 (0.49) | CA2CHRNB2CHRNA4KDM4EALDH1A1 | |
| SCHEMBL8761388 | 0.85 | CHRNB2 (0.52) | CA2CHRNB2CHRNA4KDM4EALDH1A1 | |
| SCHEMBL8761047 | 0.81 | ERN1 (0.57) | CHRNB2CHRNA4KDM4EALDH1A1LMNA | |
| SCHEMBL9293024 | 0.76 | KDM4E (0.52) | CHRNB2CHRNA4KDM4EALDH1A1KMT2A | |
| SCHEMBL4345964 | 0.74 | CA2 (0.74) | CA2KDM4EALDH1A1CA1KMT2A | |
| SCHEMBL4345961 | 0.74 | CA2 (0.74) | CA2KDM4EALDH1A1CA1KMT2A | |
| SCHEMBL7600443 | 0.73 | CA2 (0.44) | CA2KDM4EALDH1A1CA1KMT2A | |
| SCHEMBL7599962 | 0.73 | CA2 (0.44) | CA2KDM4EALDH1A1CA1KMT2A | |
| SCHEMBL7599960 | 0.73 | CA2 (0.44) | CA2KDM4EALDH1A1CA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278154-A | New vanadium complexes | ADIR ET COMPAGNIE (FR) | 1994-01-11 | — | — | US | disclosed |
| US-5266565-A | Antidiabetic | ADIR ET COMPAGNIE (FR) | 1993-11-30 | — | — | US | disclosed |