Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8761114 | 0.75 | NOTUM (0.34) | NOTUMSMN1; SMN2ALDH1A1 | |
| SCHEMBL7524485 | 0.72 | NOTUM (0.34) | KDM4ELMNANOTUMGAAALDH1A1 | |
| SCHEMBL7526227 | 0.72 | NOTUM (0.34) | KDM4ELMNANOTUMGAAALDH1A1 | |
| SCHEMBL8761988 | 0.70 | NOTUM (0.31) | NOTUM | |
| SCHEMBL9221707 | 0.65 | ATM (0.52) | KDM4ELMNACYP1A2GAAALDH1A1 | |
| SCHEMBL8762022 | 0.63 | — | — | |
| SCHEMBL8345599 | 0.63 | ALDH1A1 (0.32) | KDM4ELMNACYP1A2ALDH1A1HPGD | |
| SCHEMBL8612005 | 0.62 | TP53 (0.34) | KDM4ELMNACYP1A2NOTUMSMN1; SMN2 | |
| SCHEMBL7888968 | 0.62 | RXFP1 (0.40) | ALDH1A1MAPTTSHR | |
| SCHEMBL22495466 | 0.62 | HTT (0.40) | KDM4ELMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770067-A1 | SUBSTITUTED CINNAMIC OXIME AND HYDROXAMIDE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996002518-A1 | SUBSTITUTED CINNAMIC OXIME AND HYDROXAMIDE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |