Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15902750 | 1.00 | PARP1 (0.39) | PARP1ACHECA1CA2TSHR | |
| SCHEMBL8641995 | 0.98 | PARP1 (0.38) | PARP1ACHECA1CA2 | |
| Water SCHEMBL28329751 | 0.98 | PARP1 (0.38) | PARP1ACHECA1CA2 | |
| SCHEMBL328812 | 0.80 | — | — | |
| SCHEMBL17277710 | 0.68 | PARP1 (0.36) | PARP1CA1CA2 | |
| SCHEMBL7178787 | 0.68 | — | — | |
| SCHEMBL20511816 | 0.66 | PARP1 (0.46) | PARP1ACHECA1CA2TSHR | |
| SCHEMBL20511815 | 0.66 | PARP1 (0.46) | PARP1ACHECA1CA2TSHR | |
| SCHEMBL9388020 | 0.66 | — | — | |
| SCHEMBL31586332 | 0.66 | TRPA1 (0.50) | PARP1CA1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776489-A | The method of copper catalysis bis- sulphur -3- 40 thione derivatives of phenylpropyl alcohol ynamine sulphur Cyclization 1,2- | 温州大学 | 2019-05-21 | — | — | CN | claimed |
| US-8809010-B2 | Method for prophylactic treatment of alzheimer's disease using inhibitors of glutaminyl cyclase and glutamate cyclases | PROBIODRUG AG (DE) | 2014-08-19 | — | — | US | claimed |
| US-8338120-B2 | Anticancer agents; therapy for infections; administering glutaminyl cyclase inhibitor such as 1-(3-(1H-imidazole-1-yl)propyl)-3-(3,4-dimethoxy-phenyl)thiourea hydrochloride; Alzheimer's disease; Down syndrome; controlling fertility; schizophrenia; skin disorders; dementia | PROBIODRUG AG (DE) | 2012-12-25 | — | — | US | claimed |
| US-20120184518-A1 | METHODS OF TREATING OR PREVENTING AN INFLAMMATORY DISEASE OR CONDITION USING GLUTAMINYL CYCLASE INHIBITORS | PROBIODRUG AG (DE) | 2012-07-19 | — | — | US | claimed |
| US-7732162-B2 | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases | PROBIODRUG AG (DE) | 2010-06-08 | — | — | US | claimed |
| US-20100040575-A1 | USE OF INHIBITORS OF GLUTAMINYL CYCLASE AND GLUTAMATE CYCLASE FOR TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | PROBIODRUG AG (DE) | 2010-02-18 | — | — | US | claimed |
| CN-101490030-A | Novel benzopyran and 1, 2-benzothiopyranamide derivatives, preparation thereof and therapeutic use thereof | PF MEDICAMENT (FR) | 2009-07-22 | — | — | CN | claimed |
| CN-101460458-A | Indole-3-carboxylic acid amide, ester, thioamide and thiol ester compounds bearing aryl or heteroaryl groups having sphingosine-1-phosphate (S1P) receptor antagonist biological activity | ALLERGAN INC (US) | 2009-06-17 | — | — | CN | claimed |
| US-20090068699-A1 | USE OF GLUTAMINYL CYCLASE INHIBITORS | PROBIODRUG AG (DE) | 2009-03-12 | — | — | US | claimed |
| US-20070191366-A1 | USE OF EFFECTORS OF GLUTAMINYL AND GLUTAMATE CYCLASES | PROBIODRUG AG (DE) | 2007-08-16 | — | — | US | claimed |
| CN-1039904-C | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-09-23 | — | — | CN | claimed |
| US-20250282621-A1 | CARBON NANOTUBE COMPOSITE COMPRISING MECHANICAL L IGANDS | NANOCORE APS (DK) | 2025-09-11 | — | — | US | disclosed |
| US-12227625-B2 | Composite materials comprising mechanical ligands | NANOCORE APS (DK) | 2025-02-18 | — | — | US | disclosed |
| US-11834559-B2 | Composite materials with desired characteristics | NANOCORE APS (DK) | 2023-12-05 | — | — | US | disclosed |
| WO-2023001506-A1 | CARBON NANOTUBE COMPOSITE COMPRISING MECHANICAL LIGANDS | NANOCORE APS (DK) | 2023-01-26 | — | — | WO | disclosed |
| US-5858766-A | CONTACTING HEAVY CRUDE OIL WITH SPECIFIED BACTERIAL STRAINS TO REDUCE CONTENT OF SULFUR, NITROGEN AND TRACE METALS AND INCREASE CONTENT OF SATURATED HYDROCARBONS | BROOKHAVEN SCIENCE ASSOCIATES (US) | 1999-01-12 | — | — | US | disclosed |
| CN-1039904-C | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-09-23 | — | — | CN | disclosed |
| US-5492828-A | ENHANCED OIL RECOVERY BY GRWOING THERMOPHILIC MICROBIAL STRAINS IN A MEDIUM WHERE CRUDE OIL IS SUPPLEMENTED WITH CARBON SOURCE, ISOLATION, GROWING THEM IN A MEDIUM CONTANING CRUDE OIL AND CARBON SOURCE IN LOWER AMOUNT, | ASSOCIATED UNIVERSITIES, INC. (US) | 1996-02-20 | — | — | US | disclosed |
| CN-1104212-A | Herbicides | RHONE POULENC AGRICULTURE (GB) | 1995-06-28 | — | — | CN | disclosed |
| US-5297625-A | For the recovery of oil from an underground oil bearing reservoir | ASSOCIATED UNIVERSITIES, INC. (US) | 1994-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191366-A1 | USE OF EFFECTORS OF GLUTAMINYL AND GLUTAMATE CYCLASES | GLS, QPCT, GLS2 | PARP1 2532/4885ACHE 799/4885CA1 3219/4885 |
| US-20100040575-A1 | USE OF INHIBITORS OF GLUTAMINYL CYCLASE AND GLUTAMATE CYCLASE FOR TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | QPCT, GLS, GLUL | PARP1 2248/4885ACHE 87/4885CA1 2371/4885 |
| US-20090068699-A1 | USE OF GLUTAMINYL CYCLASE INHIBITORS | QPCT, GGCT, GLS | PARP1 1828/4885ACHE 943/4885CA1 2961/4885 |
| US-20120184518-A1 | METHODS OF TREATING OR PREVENTING AN INFLAMMATORY DISEASE OR CONDITION USING GLUTAMINYL CYCLASE INHIBITORS | QPCT, GGCT, GLUL | PARP1 564/4885ACHE 845/4885CA1 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.