Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.48 |
| ▸ | ADK | P55263 | 2/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905991 | 0.87 | KDM4E (0.53) | KDM4EPKMADK | |
| SCHEMBL1907078 | 0.80 | KDM4E (0.49) | KDM4EPKMADORA3ADKDOT1L | |
| SCHEMBL17816342 | 0.80 | ADK (0.72) | KDM4EADORA3ADKDOT1LNPC1 | |
| SCHEMBL13065703 | 0.80 | ADK (0.72) | KDM4EADORA3ADKDOT1LNPC1 | |
| SCHEMBL20419279 | 0.80 | ADK (0.72) | KDM4EADORA3ADKDOT1LNPC1 | |
| SCHEMBL18089839 | 0.79 | ADORA3 (0.73) | ADORA3 | |
| SCHEMBL2461484 | 0.79 | ADORA3 (0.73) | ADORA3 | |
| SCHEMBL10073439 | 0.79 | ADORA3 (0.73) | ADORA3 | |
| SCHEMBL2461486 | 0.79 | ADORA3 (0.73) | ADORA3 | |
| SCHEMBL14428970 | 0.79 | ADK (0.71) | KDM4EADORA3ADKDOT1LNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691980-B1 | 7-DEAZAPURINE MODIFIED OLIGONUCLEOTIDES | SANOFI SA (FR) | 1997-06-04 | — | — | EP | disclosed |
| WO-1994022892-A1 | 7-DEAZAPURINE MODIFIED OLIGONUCLEOTIDES | STERLING WINTHROP INC. (US) | 1994-10-13 | — | — | WO | disclosed |