SCHEMBL8761669

SCHEMBL8761669

C=CCC(O)(COCC)Oc1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.33
LTA4H P09960 1/20 0.32
ACSS2 Q9NR19 1/20 0.31
SMN1; SMN2 Q16637 4/20 0.30
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
KDM4E B2RXH2 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10449497 0.84 MAPT (0.41) MAPTALDH1A1TSHRHTTLTA4H
SCHEMBL7120119 0.79 ALDH1A1 (0.40) MAPTALDH1A1TSHRHTTLTA4H
SCHEMBL4882231 0.77 ALDH1A1 (0.35) MAPTALDH1A1TSHRHTTSMN1; SMN2
SCHEMBL8445973 0.76 PPARG (0.40) ALDH1A1HTTLTA4HSMN1; SMN2
SCHEMBL330343 0.76 PPARG (0.40) ALDH1A1HTTLTA4HSMN1; SMN2
SCHEMBL1811048 0.74 MAPT (0.47) MAPTALDH1A1TSHRHTTSMN1; SMN2
SCHEMBL11228914 0.71 LTA4H (0.35) ALDH1A1LTA4HSMN1; SMN2
SCHEMBL11253530 0.70 LTA4H (0.39) ALDH1A1TSHRLTA4H
SCHEMBL7594365 0.70 ALDH1A1 (0.41) MAPTALDH1A1TSHRHTTLTA4H
SCHEMBL8761683 0.70 ALDH1A1 (0.35) MAPTALDH1A1TSHRHTTLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594814-B1 METAL CARBOXYLATES OF ALKYLENE BIS-PHENOL ALKANOIC ACIDS USEFUL AS ADDITIVES FOR FUELS AND LUBRICANTS LUBRIZOL CORP (US) 1997-06-18 EP disclosed
EP-0594814-A1 METAL CARBOXYLATES OF ALKYLENE BIS-PHENOL ALKONIC ACIDS USEFUL AS ADDITIVES FOR FUELS AND LUBRICANTS. LUBRIZOL CORP (US) 1994-05-04 EP disclosed
WO-1993021143-A1 METAL CARBOXYLATES OF ALKYLENE BIS-PHENOL ALKONIC ACIDS USEFUL AS ADDITIVES FOR FUELS AND LUBRICANTS THE LUBRIZOL CORPORATION (US) 1993-10-28 WO disclosed
US-4526723-A Microbiocides UNION CARBIDE CORPORATION (US) 1985-07-02 US disclosed
US-4464524-A Polymeric thickeners and coatings containing same THE SHERWIN-WILLIAMS COMPANY (US) 1984-08-07 US disclosed
EP-0027731-B1 VAGINAL SUPPOSITORY ORTHO PHARMACEUTICAL CORPORATION (US) 1984-04-18 EP disclosed
US-4436666-A HERBICIDES, MITICIDWS UNION CARBIDE CORPORATION (US) 1984-03-13 US disclosed
US-4338122-A MITICIDES, HERBICIDES UNION CARBIDE CORPORATION (US) 1982-07-06 US disclosed
US-4338239-A COPOLYMER OF ACRYLIC OR METHACRYLIC ACID AND DERIVATIVE OF ALLYL GLYCERYL ETHER CELANESE CORPORATION (US) 1982-07-06 US disclosed
EP-0050923-A2 Polyacrylate thickening agents CELANESE CORPORATION (US) 1982-05-05 EP disclosed
US-4322399-A ALKYLPHENOXYPOLYETHOXYETHANOL, POLYOXYETHYLENE GLYCOL, FOAMING AGENT AND STABILIZERS ORTHO PHARMACEUTICAL CORPORATION (US) 1982-03-30 US disclosed
EP-0027731-A2 Vaginal suppository ORTHO PHARMACEUTICAL CORPORATION (US) 1981-04-29 EP disclosed
US-4230844-A POLYMERIZING (METH-)ACRYLIC ACID AND AN ACRYLATE MODIFIED POLYOXYETHYLENE GLYCOL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-10-28 US disclosed
US-4138381-A A,B-UNSATURATED ACID-ALKYL ACRYLATE-POLYETHER ACRYLATE TERPOLYMER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-02-06 US disclosed
US-4057506-A Heavy-duty liquid detergent COLGATE PALMOLIVE COMPANY (US) 1977-11-08 US disclosed