Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340084 | 0.88 | MAPT (0.65) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL31725934 | 0.88 | MAPT (0.65) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL16336364 | 0.86 | MAPT (0.62) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL31558251 | 0.86 | MAPT (0.62) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL28918460 | 0.84 | MAPK14 (0.50) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL27930584 | 0.83 | L3MBTL1 (0.59) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL9007487 | 0.83 | MAPT (0.80) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL27703867 | 0.81 | L3MBTL1 (0.63) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL19086324 | 0.81 | TDP1 (0.76) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL20139372 | 0.80 | TDP1 (0.54) | MAPTTDP1L3MBTL1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698580-A | TREATING DISEASES CAUSED BY RESPIRATORY SYNCYTIAL VIRUS | RATIONAL DRUG DESIGN LABORATORIES (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0770609-A1 | ANTIVIRAL AGENT CONTAINING BENZODITHIIN DERIVATIVE AS ACTIVE INGREDIENT | Rational Drug Design Laboratories (JP) | 1997-05-02 | — | — | EP | disclosed |