Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | CTSL | P07711 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 6/20 | 0.57 |
| ▸ | MMP9 | P14780 | 5/20 | 0.57 |
| ▸ | ADAMTS4 | O75173 | 5/20 | 0.55 |
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20335144 | 0.90 | CTSL (0.67) | CTSLMMP2MMP9ADAMTS4TDP1 | |
| SCHEMBL14534184 | 0.90 | CTSL (0.67) | CTSLMMP2MMP9ADAMTS4TDP1 | |
| SCHEMBL20335146 | 0.90 | CTSL (0.67) | CTSLMMP2MMP9ADAMTS4TDP1 | |
| SCHEMBL8057955 | 0.88 | TDP1 (0.62) | CTSLMMP2MMP9ADAMTS4TDP1 | |
| SCHEMBL26606026 | 0.87 | MMP9 (0.69) | CTSLMMP2MMP9ADAMTS4MMP13 | |
| SCHEMBL26606022 | 0.87 | MMP9 (0.69) | CTSLMMP2MMP9ADAMTS4MMP13 | |
| SCHEMBL20335059 | 0.85 | CTSL (0.68) | CTSLMMP2MMP9ADAMTS4MMP13 | |
| SCHEMBL20335058 | 0.85 | CTSL (0.68) | CTSLMMP2MMP9ADAMTS4MMP13 | |
| SCHEMBL27466542 | 0.84 | PPARG (0.60) | ARMMP9ITGB3ITGA2BPPARG | |
| SCHEMBL6577060 | 0.84 | PPARG (0.60) | ARMMP9ITGB3ITGA2BPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770063-A1 | TECHNETIUM-SULPHONAMIDE COMPLEXES, THEIR USE, PHARMACEUTICAL AGENTS CONTAINING THEM, AND PROCESS FOR PRODUCING THE COMPLEXES AND AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996002500-A1 | TECHNETIUM-SULPHONAMIDE COMPLEXES, THEIR USE, PHARMACEUTICAL AGENTS CONTAINING THEM, AND PROCESS FOR PRODUCING THE COMPLEXES AND AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |