Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.39 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762846 | 0.90 | LMNA (0.42) | SMURF2SMURF1DPP4DPP7NR1H4 | |
| SCHEMBL8488733 | 0.88 | POLB (0.36) | DPP4DPP7GPBAR1THRBNR1H4 | |
| SCHEMBL8492339 | 0.81 | NPC1 (0.39) | DPP4DPP7GPBAR1NR1H4ALDH1A1 | |
| SCHEMBL8489321 | 0.81 | GLP1R (0.39) | NR1H4ALDH1A1POLBKMT2A | |
| SCHEMBL8763725 | 0.80 | SMURF2 (0.39) | SMURF2SMURF1GPBAR1NR1H4 | |
| SCHEMBL8492902 | 0.80 | NPC1 (0.38) | DPP4DPP7NR1H4KMT2A | |
| SCHEMBL8492682 | 0.80 | SMURF2 (0.40) | SMURF2SMURF1GPBAR1NR1H4ALDH1A1 | |
| SCHEMBL8489354 | 0.80 | THRB (0.37) | DPP4DPP7THRBPTGDR2ALDH1A1 | |
| SCHEMBL8494679 | 0.80 | NR1H4 (0.40) | NR1H4ALDH1A1POLBKMT2A | |
| SCHEMBL27338623 | 0.78 | PPARG (0.38) | SMURF2SMURF1GPBAR1NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040940-C | Composition containing 4-benzoyl isoxazole derivative and application thereof | RHONE POULENE AGRICULTURE LTD (GB) | 1998-12-02 | — | — | CN | claimed |
| EP-0487357-B1 | 4 Benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-07-02 | — | — | EP | claimed |
| CN-1061596-A | 4-Benzoylisoxazole Derivatives | RHONE POULENC AGRICULTURE (GB) | 1992-06-03 | — | — | CN | claimed |
| CN-1093537-C | Process for preparing composition contg. 4 -benzoyl-iso-oxazole derivs. | PHONE POULENC AGRICULTURE LTD (GB) | 2002-10-30 | — | — | CN | disclosed |
| CN-1040940-C | Composition containing 4-benzoyl isoxazole derivative and application thereof | RHONE POULENE AGRICULTURE LTD (GB) | 1998-12-02 | — | — | CN | disclosed |
| CN-1183411-A | Process for preparing composition contg. 4 -benzoyl-iso-oxazole derivs. | RHONE POULENC AGRICULTURE (GB) | 1998-06-03 | — | — | CN | disclosed |