SCHEMBL876292

SCHEMBL876292

O=C1CC(C(=O)c2ccccc2)C(=O)N1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.51
DDB1 Q16531 3/20 0.46
CRBN Q96SW2 3/20 0.46
MCL1 Q07820 1/20 0.46
MAPT P10636 1/20 0.43
ALOX15 P16050 1/20 0.43
HTT P42858 1/20 0.43
HBB P68871 1/20 0.43
KDM4E B2RXH2 1/20 0.42
PKM P14618 1/20 0.42
POLB P06746 2/20 0.41
IDO1 P14902 1/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4C Q9H3R0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28650761 0.98 ALDH1A1 (0.50) ALDH1A1DDB1CRBNMCL1MAPT
SCHEMBL44224 0.92 ALDH1A1 (0.45) ALDH1A1DDB1CRBNMCL1MAPT
SCHEMBL31220632 0.84 ALDH1A1 (0.47) ALDH1A1DDB1CRBNHTTKDM4E
SCHEMBL6332550 0.84 MCL1 (0.49) ALDH1A1DDB1CRBNMCL1MAPT
SCHEMBL9386437 0.82 ALDH1A1 (0.45) ALDH1A1DDB1CRBNKDM4EPKM
SCHEMBL30431491 0.82 ALDH1A1 (0.49) ALDH1A1DDB1CRBNMCL1MAPT
SCHEMBL5042931 0.82 CES2 (0.41) DDB1CRBNIDO1
SCHEMBL14331806 0.82 CRBN (0.63) ALDH1A1DDB1CRBNMCL1POLB
SCHEMBL25263449 0.80 ALDH1A1 (0.44) ALDH1A1DDB1CRBNMAPTHTT
SCHEMBL30462621 0.80 MAPT (0.46) ALDH1A1MCL1MAPTALOX15HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448965-A1 MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF Angiochem Inc. (CA) 2012-05-09 EP claimed
WO-2011000095-A1 MULTIMERIC PEPTIDE CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2011-01-06 WO claimed
US-12458705-B2 Antibody-oligonucleotide conjugates ANGIEX, INC. (US) 2025-11-04 US disclosed
US-12428477-B2 Antibody-drug conjugates comprising anti-TM4SF1 antibodies and methods of using the same ANGIEX, INC. (US) 2025-09-30 US disclosed
US-20250296957-A1 PEPTIDE COMPOUNDS AND PEPTIDE CONJUGATES FOR THE TREATMENT OF CANCER THROUGH RECEPTOR-MEDIATED CHEMOTHERAPY TRANSFERT PLUS, S.E.C. (CA) 2025-09-25 US disclosed
EP-4619041-A1 DRUG CONJUGATE COMPOUNDS FOR STIMULATING THE ANTITUMOR IMMUNE RESPONSE THERATECHNOLOGIES INC. (CA) 2025-09-24 EP disclosed
EP-3925969-B1 PEPTIDE COMPOUNDS AND PEPTIDE CONJUGATES FOR THE TREATMENT OF CANCER THROUGH RECEPTOR-MEDIATED CHEMOTHERAPY TRANSFERT PLUS SEC (CA) 2025-09-03 EP disclosed
EP-3350333-B2 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION MODERNATX INC (US) 2025-08-06 EP disclosed
US-20250186624-A1 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION ARES CAPITAL CORPORATION, AS AGENT 2025-06-12 US disclosed
US-20250152730-A1 ANTI-TM4SF1 ANTIBODY-DRUG CONJUGATES COMPRISING CLEAVABLE LINKERS AND METHODS OF USING SAME ANGIEX, INC. 2025-05-15 US disclosed
EP-4536290-A1 ANTI-TM4SF1 ANTIBODY-DRUG CONJUGATES COMPRISING CLEAVABLE LINKERS AND METHODS OF USING SAME Angiex, Inc. (US) 2025-04-16 EP disclosed
EP-0063017-A1 Detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-20 EP disclosed
EP-0062523-A2 Detergent additive compositions and preparations and use thereof in detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-10-13 EP disclosed
EP-0051987-A1 Bleach activator compositions, preparation thereof and use in granular detergent compositions THE PROCTER & GAMBLE COMPANY (US) 1982-05-19 EP disclosed
US-4321157-A SILICA OR SILICATE, ORGANIC PEROXY ACID BLEACH PRECURSOR, ALIPHATIC ALCOHOL-ALKYLENE OXIDE CONDENSATE NONIONIC SURFACTANT THE PROCTER & GAMBLE COMPANY (US) 1982-03-23 US disclosed
EP-0034387-A2 Mulls containing chain structure clay suspension aids THE PROCTER & GAMBLE COMPANY (US) 1981-08-26 EP disclosed
EP-0028432-A1 Granular laundry compositions THE PROCTER & GAMBLE COMPANY (US) 1981-05-13 EP disclosed
US-4264466-A LAUNDRY DETERGENTS THE PROCTER & GAMBLE COMPANY (US) 1981-04-28 US disclosed
US-4248928-A TETRAACETYL AKYLENEDIAMINES OR TETRAACETYL GLYCOURIL PEROXY BLEACH PRECURSOR THE PROCTER & GAMBLE COMPANY (US) 1981-02-03 US disclosed
US-4179390-A Laundry additive product THE PROCTER & GAMBLE COMPANY (US) 1979-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428477-B2 Antibody-drug conjugates comprising anti-TM4SF1 antibodies and methods of using the same TM9SF4, TM9SF2, TM9SF3 ALDH1A1 2725/4885DDB1 1008/4885CRBN 2679/4885
US-20250296957-A1 PEPTIDE COMPOUNDS AND PEPTIDE CONJUGATES FOR THE TREATMENT OF CANCER THROUGH RECEPTOR-MEDIATED CHEMOTHERAPY NGLY1, VIP, NPY1R ALDH1A1 4790/4885DDB1 983/4885CRBN 793/4885
US-20250186624-A1 POLYNUCLEOTIDES CONTAINING A STABILIZING TAIL REGION POLR2E, POLN, PHAX ALDH1A1 4559/4885DDB1 181/4885CRBN 2700/4885
US-12458705-B2 Antibody-oligonucleotide conjugates TM9SF4, TMSB4X, IGSF11 ALDH1A1 4144/4885DDB1 747/4885CRBN 2271/4885
US-20250152730-A1 ANTI-TM4SF1 ANTIBODY-DRUG CONJUGATES COMPRISING CLEAVABLE LINKERS AND METHODS OF USING SAME TM9SF4, TM9SF2, TMPRSS4 ALDH1A1 2608/4885DDB1 798/4885CRBN 2365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.