Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763176 | 0.87 | HSD17B10 (0.42) | ALDH1A1MAPTHSD17B10NPC1GAA | |
| SCHEMBL7050113 | 0.76 | HSD17B10 (0.44) | CAPN1CTSBALDH1A1MAPTANPEP | |
| SCHEMBL8529950 | 0.74 | PRNP (0.40) | CAPN1CTSBALDH1A1MAPTANPEP | |
| SCHEMBL7050118 | 0.74 | ALDH1A1 (0.34) | CAPN1CTSBALDH1A1MAPTPOLB | |
| SCHEMBL27041447 | 0.73 | CYP3A4 (0.52) | ALDH1A1MAPTPOLBANPEPEPHX1 | |
| SCHEMBL8529953 | 0.72 | ANPEP (0.36) | CAPN1CTSBALDH1A1MAPTPOLB | |
| SCHEMBL7905195 | 0.71 | EPHX1 (0.65) | ALDH1A1MAPTPOLBEPHX1KDM4E | |
| SCHEMBL8529947 | 0.71 | CYP3A4 (0.41) | CAPN1CTSBALDH1A1MAPTPOLB | |
| SCHEMBL7050341 | 0.70 | CYP3A4 (0.39) | CAPN1CTSBALDH1A1MAPTPOLB | |
| SCHEMBL8528855 | 0.69 | HSD17B10 (0.35) | ALDH1A1HSD17B10NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726903-A1 | MATRIX METALLOPROTEASE INHIBITORS | SYNTEX INC (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995012603-A1 | MATRIX METALLOPROTEASE INHIBITORS________________________________ | SYNTEX (U.S.A.) INC. (US) | 1995-05-11 | — | — | WO | disclosed |