SCHEMBL8763477

SCHEMBL8763477

CCCc1oc(CCC)c2ccccc12

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
HPGD P15428 3/20 0.43
KDM4E B2RXH2 2/20 0.43
GAA P10253 1/20 0.43
ELANE P08246 1/20 0.43
CYP2C9 P11712 4/20 0.41
PBRM1 Q86U86 1/20 0.38
PTPN1 P18031 2/20 0.37
MAPT P10636 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
RAB9A P51151 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
EYA3 Q99504 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9738369 0.89 CYP2C9 (0.39) ALDH1A1HPGDKDM4EGAAELANE
SCHEMBL8763449 0.86 PTPN1 (0.49) PBRM1PTPN1MAPTEYA3
SCHEMBL11880429 0.84 MAPT (0.47) PTPN1MAPTRAB9AEYA3
SCHEMBL8762701 0.79 EYA3 (0.41) ALDH1A1HPGDCYP2C9PBRM1PTPN1
SCHEMBL11402772 0.74 PTPN1 (0.50) ALDH1A1HPGDKDM4EGAACYP2C9
SCHEMBL793212 0.74 CYP2C9 (0.48) KDM4ECYP2C9PTPN1RAB9AALKBH5
SCHEMBL11822414 0.73 CYP2C9 (0.47) ALDH1A1KDM4ECYP2C9PTPN1MAPT
SCHEMBL28872356 0.72 ELANE (0.49) ALDH1A1HPGDKDM4EGAAELANE
SCHEMBL13183865 0.72 KDM4E (0.41) ALDH1A1HPGDKDM4EGAAELANE
SCHEMBL16783818 0.71 ELANE (0.47) ALDH1A1ELANECYP2C9PBRM1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605127-B1 Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules XEROX CORP (US) 1997-07-02 EP disclosed
US-5401615-A Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules XEROX CORPORATION (US) 1995-03-28 US disclosed
EP-0605127-A1 Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules XEROX CORPORATION (US) 1994-07-06 EP disclosed
EP-0186303-B1 ELECTROPHOTOGRAPHIC IMAGING MEMBERS XEROX CORPORATION (US) 1989-06-07 EP disclosed
US-4599286-A ELECTROGRAPHY XEROX CORPORATION (US) 1986-07-08 US disclosed
EP-0186303-A1 Electrophotographic imaging members XEROX CORPORATION (US) 1986-07-02 EP disclosed