Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 3/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28886362 | 0.85 | CYP2C19 (0.37) | EYA3SLC22A12TP53CYP2C19CYP2C9 | |
| SCHEMBL14614234 | 0.80 | EYA3 (0.34) | EYA3SLC22A12TP53CYP2C19CYP2C9 | |
| SCHEMBL8763477 | 0.79 | ALDH1A1 (0.43) | EYA3CYP2C9MEN1KMT2AALDH1A1 | |
| SCHEMBL8763449 | 0.75 | PTPN1 (0.49) | EYA3TTRMAPTPTPN1PBRM1 | |
| SCHEMBL11880429 | 0.74 | MAPT (0.47) | EYA3CYP2C19LMNACYP1A2MAPT | |
| SCHEMBL10238814 | 0.72 | CYP2C19 (0.49) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| SCHEMBL5860509 | 0.72 | EYA3 (0.49) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| SCHEMBL23435971 | 0.71 | EYA3 (0.47) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| SCHEMBL14156776 | 0.71 | EYA3 (0.47) | EYA3SLC22A12CYP2C19CYP2C9MEN1 | |
| SCHEMBL9738369 | 0.71 | CYP2C9 (0.39) | EYA3CYP2C9ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605127-B1 | Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules | XEROX CORP (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5401615-A | Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules | XEROX CORPORATION (US) | 1995-03-28 | — | — | US | disclosed |
| EP-0605127-A1 | Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules | XEROX CORPORATION (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0186303-B1 | ELECTROPHOTOGRAPHIC IMAGING MEMBERS | XEROX CORPORATION (US) | 1989-06-07 | — | — | EP | disclosed |
| US-4599286-A | ELECTROGRAPHY | XEROX CORPORATION (US) | 1986-07-08 | — | — | US | disclosed |
| EP-0186303-A1 | Electrophotographic imaging members | XEROX CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |