SCHEMBL8763449

SCHEMBL8763449

CCCCc1oc(CCCC)c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 7/20 0.49
EYA3 Q99504 2/20 0.46
TTR P02766 1/20 0.42
MAPT P10636 1/20 0.41
TLR8 Q9NR97 2/20 0.41
PBRM1 Q86U86 1/20 0.41
TLR7 Q9NYK1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11880429 0.93 MAPT (0.47) PTPN1EYA3MAPT
SCHEMBL8763477 0.86 ALDH1A1 (0.43) PTPN1EYA3MAPTPBRM1
SCHEMBL27494718 0.79 PTPN1 (0.46) PTPN1EYA3TTRMAPT
SCHEMBL8544529 0.78 MAPT (0.38) PTPN1EYA3MAPTTLR8
SCHEMBL9738369 0.77 CYP2C9 (0.39) PTPN1EYA3PBRM1
SCHEMBL6718612 0.77 PTPN1 (0.56) PTPN1EYA3TTR
SCHEMBL8762701 0.75 EYA3 (0.41) PTPN1EYA3TTRMAPTPBRM1
SCHEMBL28018757 0.75 PTPN1 (0.55) PTPN1EYA3TTR
SCHEMBL31314629 0.75 EYA3 (0.56) PTPN1EYA3TTR
SCHEMBL16684493 0.74 MAPT (0.43) PTPN1EYA3MAPTTLR8TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0605127-B1 Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules XEROX CORP (US) 1997-07-02 EP disclosed
US-5401615-A Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules XEROX CORPORATION (US) 1995-03-28 US disclosed
EP-0605127-A1 Overcoating for multilayered organic photoreceptors containing a stabilizer and charge transport molecules XEROX CORPORATION (US) 1994-07-06 EP disclosed
EP-0186303-B1 ELECTROPHOTOGRAPHIC IMAGING MEMBERS XEROX CORPORATION (US) 1989-06-07 EP disclosed
US-4599286-A ELECTROGRAPHY XEROX CORPORATION (US) 1986-07-08 US disclosed
EP-0186303-A1 Electrophotographic imaging members XEROX CORPORATION (US) 1986-07-02 EP disclosed