Methacrylic Acid

Methacrylic Acid

SCHEMBL8763528

C=C(C)C(=O)O.CC(=CCCO)C(=O)O.CC(=CCCc1ccccc1)C(=O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.43
ALDH1A1 P00352 3/20 0.41
CYP2C9 P11712 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
GPR52 Q9Y2T5 6/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
AKR1C3 P42330 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
HPGD P15428 1/20 0.37
TRPV1 Q8NER1 2/20 0.36
KEAP1 Q14145 1/20 0.36
LTB4R Q15722 1/20 0.36
LTB4R2 Q9NPC1 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL3241427 0.88 CYP2C9 (0.40) GRIK1ALDH1A1CYP2C9TDP1SMN1; SMN2
SCHEMBL197321 0.87 GRIK1 (0.53) GRIK1ALDH1A1CYP2C9GPR52SMN1; SMN2
SCHEMBL197322 0.87 GRIK1 (0.53) GRIK1ALDH1A1CYP2C9GPR52SMN1; SMN2
Methacrylic Acid SCHEMBL8762467 0.86 GRIK1 (0.42) GRIK1ALDH1A1CYP2C9GPR52SMN1; SMN2
Methacrylic Acid SCHEMBL8763652 0.82 GRIK1 (0.42) GRIK1ALDH1A1CYP2C9TDP1GPR52
Methacrylic Acid SCHEMBL3667825 0.82 CD81 (0.37)
SCHEMBL1920796 0.81 LMNA (0.51) GRIK1ALDH1A1CYP2C9GPR52SMN1; SMN2
SCHEMBL444701 0.81 LMNA (0.51) GRIK1ALDH1A1CYP2C9GPR52SMN1; SMN2
Styrene SCHEMBL21113739 0.81 AKR1C3 (0.39) ALDH1A1CYP2C9SMN1; SMN2AKR1C3NPC1
SCHEMBL29349872 0.81 HCAR2 (0.43) GRIK1ALDH1A1TDP1SMN1; SMN2AKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0626977-B1 ABC TRIBLOCK METHACRYLATE POLYMERS DU PONT (US) 1997-07-09 EP claimed
WO-1993017057-A1 ABC TRIBLOCK METHACRYLATE POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-02 WO claimed
US-5219945-A Having each block different, at least one hydrophilic and one hydrophobic E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-15 US claimed
EP-0626977-B1 ABC TRIBLOCK METHACRYLATE POLYMERS DU PONT (US) 1997-07-09 EP disclosed
WO-1993017057-A1 ABC TRIBLOCK METHACRYLATE POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-02 WO disclosed
US-5219945-A Having each block different, at least one hydrophilic and one hydrophobic E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-15 US disclosed