Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 6/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444701 | 1.00 | LMNA (0.51) | LMNAGRIK1ALDH1A1TBXAS1CYP2C9 | |
| SCHEMBL197321 | 0.93 | GRIK1 (0.53) | GRIK1ALDH1A1CYP2C9GPR52AKR1C3 | |
| SCHEMBL197322 | 0.93 | GRIK1 (0.53) | GRIK1ALDH1A1CYP2C9GPR52AKR1C3 | |
| SCHEMBL1920266 | 0.87 | FFAR1 (0.51) | LMNAGRIK1GPR52FFAR1SMN1; SMN2 | |
| SCHEMBL1920269 | 0.87 | FFAR1 (0.51) | LMNAGRIK1GPR52FFAR1SMN1; SMN2 | |
| SCHEMBL11892322 | 0.84 | TRPV1 (0.53) | LMNAGRIK1ALDH1A1CYP2C9GPR52 | |
| SCHEMBL970817 | 0.83 | KDM4E (0.47) | LMNAGRIK1ALDH1A1TBXAS1 | |
| SCHEMBL1919934 | 0.83 | GPR52 (0.50) | GRIK1GPR52FFAR1 | |
| SCHEMBL440430 | 0.83 | THRB (0.46) | GRIK1ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL1574137 | 0.83 | HDAC3 (0.48) | GRIK1ALDH1A1TBXAS1CYP2C9AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| EP-3728339-B1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | AMO Ireland (IE) | 2022-07-06 | — | — | EP | claimed |
| EP-2303331-B1 | OPHTHALMIC DEVICE HAVING THERAPEUTIC AGENT DELIVERY CAPABILITY AND METHOD OF FORMING SAME | ALCON INC (CH) | 2022-01-26 | — | — | EP | claimed |
| EP-3200840-B1 | LOW-WATER CONTENT ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | ALCON INC (CH) | 2021-11-17 | — | — | EP | claimed |
| EP-3200839-B1 | HYDROPHOBIC ACRYLATE-ACRYLAMIDE COPOLYMERS FOR OPHTHALMIC DEVICES | NOVARTIS AG (CH) | 2019-09-04 | — | — | EP | claimed |
| EP-3223870-B1 | WET-PACK INTRAOCULAR LENS MATERIALS WITH HIGH REFRACTIVE INDEX | NOVARTIS AG (CH) | 2018-09-26 | — | — | EP | claimed |
| EP-3077016-B1 | SOFT ACRYLIC MATERIALS WITH HIGH REFRACTIVE INDEX AND MINIMIZED GLISTENING | NOVARTIS AG (CH) | 2018-05-16 | — | — | EP | claimed |
| EP-2292672-B1 | Biocompatible polymers and co-polymers comprising amino acids in the side chain | CIS PHARMA AG (CH) | 2018-05-09 | — | — | EP | claimed |
| EP-1888660-B1 | BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN | CIS PHARMA AG (CH) | 2017-05-17 | — | — | EP | claimed |
| EP-2341102-B1 | Thermoplastic resin composition revealing improved impact strength and melt flow property | CHEIL IND INC (KR) | 2015-12-02 | — | — | EP | claimed |
| EP-2268709-B1 | SCRATCH RESISTANT THERMOPLASTIC RESIN COMPOSITION | CHEIL IND INC (KR) | 2013-10-02 | — | — | EP | claimed |
| EP-2222786-B1 | SCRATCH-RESISTANT FLAMEPROOF THERMOPLASTIC RESIN COMPOSITION WITH IMPROVED COMPATIBILITY | CHEIL IND INC (KR) | 2013-01-02 | — | — | EP | claimed |
| EP-2204412-B1 | Polycarbonate resin composition with improved scratch resistance and melt flow index | CHEIL IND INC (KR) | 2012-08-29 | — | — | EP | claimed |
| EP-2341102-A1 | Thermoplastic resin composition revealing improved impact strength and melt flow property | Cheil Industries Inc. (KR) | 2011-07-06 | — | — | EP | claimed |
| US-20110160377-A1 | Thermoplastic Resin Composition Having Improved Impact Strength and Melt Flow Properties | CHEIL INDUSTRIES INC. (KR) | 2011-06-30 | — | — | US | claimed |
| EP-2225325-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON INC (CH) | 2011-06-01 | — | — | EP | claimed |
| EP-1080382-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS | ALCON INC (CH) | 2009-07-08 | — | — | EP | claimed |
| EP-1664855-B1 | PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS | BAUSCH & LOMB (US) | 2009-03-11 | — | — | EP | claimed |
| EP-1177227-B1 | WATER PLASTICIZED HIGH REFRACTIVE INDEX POLYMER FOR OPHTHALMIC APPLICATIONS | SURGIDEV CORP (US) | 2003-10-01 | — | — | EP | claimed |
| EP-0914169-B1 | MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES | ALCON LAB INC (US) | 2003-07-30 | — | — | EP | claimed |