Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.32 |
| ▸ | GABRD | O14764 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.32 |
| ▸ | GABRE | P78334 | 2/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246455 | 0.67 | — | — | |
| SCHEMBL29733309 | 0.63 | CYP1A2 (0.46) | CYP1A2GABRA5GABRB2HSD17B10GABRA1 | |
| SCHEMBL11411846 | 0.62 | — | — | |
| SCHEMBL16458540 | 0.62 | CYP1A2 (0.37) | CYP1A2GABRA5GABRB2HSD17B10 | |
| SCHEMBL11035427 | 0.61 | — | — | |
| SCHEMBL11564617 | 0.60 | CYP1A2 (0.46) | CYP1A2GABRA5GABRB2HSD17B10KDM4E | |
| SCHEMBL1417449 | 0.60 | NOS1 (0.43) | CYP1A2GABRA5GABRB2HSD17B10GABRR1 | |
| SCHEMBL29904961 | 0.60 | CYP1A2 (0.39) | CYP1A2GABRA5GABRB2HSD17B10GABRP | |
| SCHEMBL1686855 | 0.60 | F2 (0.70) | HSD17B10F2 | |
| SCHEMBL4860930 | 0.60 | GABRA5 (0.44) | CYP1A2GABRA5GABRB2HSD17B10GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560365-B1 | Cephalosporin derivative | MEIJI SEIKA KAISHA (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0590681-B1 | A process for the preparation of aminothiadiazolylacetyl halide derivatives | EISAI KAGAKU KK (JP) | 1997-07-09 | — | — | EP | disclosed |
| US-5607927-A | ANTIBIOTIC BACTERICIDE | MEIJI SEIKA KAISHA, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| US-5464829-A | Cephalosporin derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| US-5428173-A | Halogenating corresponding aminothiadiazolylacetic acid | EISAI CHEMICAL CO., LTD. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0605836-A1 | Cephalosporin derivatives | MEIJI SEIKA KAISHA LTD. (JP) | 1994-07-13 | — | — | EP | disclosed |
| EP-0590681-A2 | A process for the preparation of aminothiadiazolylacetyl halide derivatives | EISAI CHEMICAL CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |
| EP-0560365-A1 | Cephalosporin derivative | MEIJI SEIKA KAISHA LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4626535-A | Cephalosporins | BAYER AKTIENGESELLSCHAFT (DE) | 1986-12-02 | — | — | US | disclosed |